Where to Find the Specific Functions of Metabolites, Such as Their Impact on Plasma Membrane Integrity
To investigate the specific functions of metabolites, including their potential influence on cellular processes such as plasma membrane integrity, the following databases are valuable resources:
1. KEGG Pathway Database (KEGG)
A comprehensive database that provides detailed information on genes, chemical compounds, enzymatic reactions, and biological pathways. The KEGG pathway module is particularly useful for elucidating the roles of metabolites within cellular metabolism and biochemical networks.
2. Human Metabolome Database (HMDB)
A specialized and extensive resource focused on human metabolites, offering detailed data on their chemical characteristics, metabolic pathways, and concentration profiles under both healthy and pathological conditions.
3. PubChem
A widely-used chemical database maintained by the U.S. National Center for Biotechnology Information (NCBI), which provides in-depth information on molecular properties, biological activities, and pharmacological functions of compounds.
4. MetaboLights
A curated repository for metabolomics experiments, offering access to annotated data on metabolites and their experimental applications across various biological contexts.
These databases collectively provide extensive functional information on metabolites. However, comprehensive understanding of metabolite-specific roles typically requires integration of experimental evidence, bioinformatics analysis, and thorough review of relevant scientific literature.
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