Comprehensive Peptide Mapping Service

Peptide mapping is a powerful technique for identifying and characterizing proteins. By integrating mass spectrometry (MS) and liquid chromatography (LC), peptide mapping analysis can deliver the following key insights: (1) Amino Acid Sequence of Proteins: Peptide mapping can elucidate the amino acid sequence of proteins by analyzing the peptides produced from enzymatic digestion. (2) Protein Modifications: Detection of post-translational modifications, including phosphorylation and glycosylation. (3) Protein Purity and Integrity: Identification of impurities and degradation products within protein samples. (4) Protein Structural Information: Determination of disulfide bond positions and protein folding states.

 



Figure 1. The Workflow of Peptide Mapping

 

MtoZ Biolabs has advanced laboratory equipment and a professional technical team dedicated to providing you with high-quality services to meet your various needs in peptide mapping research. Our goal is to support and promote the development of proteomics research by providing high-quality peptide mapping data analysis, exploring the unknown realms of life sciences. Contact us for a free consultation to learn more details!

 

Service Advantages

1. High Sensitivity and Specificity

We offer high sensitivity and specificity, enabling the detection of trace peptides and protein modifications.

 

2. High Throughput and Efficiency

We combine liquid chromatography with mass spectrometry to facilitate the rapid processing of large sample volumes.

 

3. Comprehensive Protein Characterization

We provide detailed protein information, including sequence, modifications, purity, and structural details.

 

4. Data Reliability and Accuracy

Our state-of-the-art mass spectrometers and advanced data processing software ensure high reliability and accuracy.

 

5. Customized Service

We offer tailored peptide mapping solutions to meet specific customer requirements.

 

Applications

1. Protein Identification

By enzymatically digesting protein samples to generate peptides and  analyzing the mass-to-charge ratio (m/z) of these peptides using a mass spectrometer, the protein identity can be determined by comparing the data with known protein sequences in databases.

 

2. Protein Modification Studies

Peptide mapping can accurately detect and locate various post-translational modifications (PTMs) on proteins, helping to study the impact of these modifications on protein function.

 

3. Clinical Diagnostics

By analyzing peptides in body fluids, biomarkers associated with specific diseases can be discovered for early diagnosis and disease monitoring.

 

Deliverables

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Detailed Information on Peptide Mapping Analysis

4. Mass Spectrometry Images

5. Raw Data