Different Species Sequencing Service

Antibodies, as highly specific biomolecules, are indispensable in medical research, clinical diagnostics, and therapy. Antibodies from a range of species, from traditional sources like mice, rabbits, and rats to unconventional ones like hamsters, cattle, and camelids, display unique structural and functional characteristics. For instance, single-domain antibodies from camelids offer higher permeability and stability compared to full-length antibodies from traditional mammals, while rabbit antibodies often show exceptionally high specificity and affinity.

 

MtoZ Biolabs harnesses this diversity, offering different species sequencing services, thus aiding researchers and clinicians in obtaining precise structural and functional insights into antibodies. Our platform functions independently of pre-existing databases, utilizing advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS) along with sophisticated machine learning algorithms. This autonomous approach enables us to accurately identify and sequence antibodies from various species, ensuring high-precision sequencing even in the absence of genomic data.

 

Service Advantages

High Efficiency: LC-MS/MS technology boosts sample processing speed and throughput, enabling rapid handling and quick results.

 

Broad Adaptability: Capable of high-precision sequencing for various species, including mice, humans, and camels, without relying on existing genomic or proteomic databases.

 

High Accuracy: Advanced mass spectrometry combined with bioinformatics ensures precise sequencing, accurately identifying amino acid sequences and reconstructing protein structures.

 

Applications

1. New Drug Development

By analyzing antibodies from different species, we assist drug developers in discovering new therapeutic targets, facilitating the development of innovative treatments.

 

2. Disease Diagnostics

Utilizing specific antibodies to study disease markers enhances the capability for early disease diagnosis, improving patient outcomes.

 

3. Biotechnological Research

Sequencing antibodies from various species can uncover interspecies differences in immune mechanisms, advancing fundamental scientific research.

 

4. Antibody Engineering

Providing essential sequence information for antibody modification and humanization, we help optimize antibody design for enhanced therapeutic efficacy.

 

Deliverables

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Detailed Information on Different Species Sequences

4. Mass Spectrometry Images

5. Raw Data