Resources

Proteomics Databases



Metabolomics Databases

• • 16S rRNA Sequencing Bacterial Identification

  16S rRNA sequencing bacterial identification is a molecular biology-based method for classifying and identifying microorganisms. By analyzing the specific sequences of the bacterial 16S rRNA gene, scientists can efficiently and accurately identify microbial populations. The 16S rRNA gene is a conserved ribosomal RNA sequence, stable in its molecular structure across evolution, and is present in nearly all bacteria. Its length is approximately 1500 base pairs. Regions of this gene, such as the V3-V4 r......

• • Single Cell Transcriptomics

  Single cell transcriptomics refers to the technique of analyzing gene expression at the single-cell level using sequencing technologies. This method captures the mRNA molecules from individual cells and converts them into sequencing data, offering an accurate representation of the gene expression profile within each cell. The advent of single cell transcriptomics addresses the challenge of cell-to-cell heterogeneity, which is often masked by the averaging effects seen in traditional transcriptomics a......

• • MALDI-TOF Bacteria Identification

  Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Bacterial Identification (MALDI-TOF bacteria identification) is an efficient technique based on protein mass spectrometry fingerprinting for microbial identification. By analyzing the mass-to-charge ratio (m/z) of specific proteins within microorganisms, it enables the rapid and accurate identification of bacteria, fungi, and other microbes. Unlike traditional methods, such as culturing and molecular biology techniques, MALD......

• • Protein Conformation

  Protein conformation refers to the specific three-dimensional folding and shape of a protein molecule. Proteins are long-chain molecules formed by amino acids linked through peptide bonds. These chains spontaneously fold into distinct three-dimensional structures within cells or extracellular environments. The folding process is driven by the intrinsic properties of the amino acid sequence and influenced by environmental factors. The stability and accuracy of protein conformation are critical for nor......

• • Droplet Sequencing

  Droplet sequencing is a high-throughput sequencing technology that enables single-cell or single-molecule analysis within small droplets, significantly enhancing sequencing sensitivity and resolution. It has broad applications in biomedical research, particularly in oncology, immunology, and developmental biology. By analyzing gene expression at the single-cell level, researchers can precisely characterize tumor heterogeneity and identify rare cell populations and drug-resistant cells in cancer. In i......

• • High Throughput Drug Discovery

  High throughput drug discovery (HTDD) is a technology designed to rapidly screen large compound libraries to identify potential drug candidates. The key to this technology is the use of automated experimental systems, miniaturized assay techniques, and advanced data analytics, which allow researchers to test thousands of compounds for biological activity with high speed and precision. Traditional drug discovery methods typically require years of research and substantial financial resources. In contra......

• • High Throughput Screening Drug Discovery

  High throughput screening drug discovery (HTS) is a technology that uses automation and miniaturized experimental techniques to rapidly evaluate large libraries of compounds, assessing their effects on specific biological targets. The primary purpose of HTS is to swiftly identify promising drug candidates, thereby accelerating the drug discovery process. In traditional drug discovery, researchers must evaluate the biological activity of compounds individually, a process that is time-consuming, labor-......

• • Antibody Drug Discovery

  Antibody drug discovery refers to the process of researching and developing novel antibodies for the treatment of various diseases. Antibodies are proteins produced by B cells that specifically bind to distinct antigens, neutralizing pathogens or marking them for immune system recognition. The primary goal of antibody drug discovery is to harness the specificity and high affinity of antibodies to develop drugs capable of precisely targeting diseased cells or pathogens. Compared to traditional small-m......

• • Small Molecule Drug Discovery

  Small molecule drug discovery refers to the process of identifying, optimizing, and developing small molecules with therapeutic potential using scientific methods and technologies. Small molecules typically have a low molecular weight (usually less than 900 Daltons), which allows them to easily penetrate cell membranes and bind to intracellular targets, thereby exerting their therapeutic effects. The process of small molecule drug discovery generally involves several stages, including target identifi......

• • Isotope Labeling

  Isotope Labeling is a powerful technique for introducing stable isotopes into biomolecules, enabling the investigation of dynamic changes and interactions in proteins, metabolites, and other biological molecules. In proteomics, isotope labeling is widely employed to quantify protein expression, analyze post-translational modifications, and trace metabolic pathways. By labeling proteins in distinct samples (e.g., treatment and control groups), this method allows for precise differentiation and quantif......