Resources
Proteomics Databases
Metabolomics Databases
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• Principle of Molecular Weight Determination in Glycosylation Site Identification
Biological drugs, as an important means of treating diseases, have drawn increasing attention. Among these complex protein drugs, glycosylation is a common post-translational modification that can affect the structure and function of drugs. Glycosylation sites, as specific amino acid residues that bind to sugar chains, play an important role in the stability, biological activity, and immunogenicity of drugs.
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• Comprehensive Analysis of New Antigen Screening Processes
Immunotherapy activates the patient's own immune system to actively attack cancer cells, bringing new hope for cancer patients. In personalized immunotherapy, the screening process for neoantigens is particularly important.
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• New Strategies and Discoveries in Protein Disulfide Bonds via Mass Spectrometry
"If each person's body is regarded as a bustling city, then proteins are the foundation that constructs this city." This is a commonly used praise for proteins. Within protein molecules, there is a special structure called a disulfide bond, which plays a crucial role in maintaining the stability and functionality of proteins.
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• Mass Spectrometry Protein Analysis Revealing Protein Composition and Function
Proteins within organisms are the fundamental elements that constitute cells and tissues, as well as the executors of various biological processes. Mass spectrometry (MS) protein analysis, as a powerful proteomics technique, can comprehensively and deeply analyze the composition and function of proteins, providing strong support for biological product development and disease research.
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• How Does Endogenous Mass Spectrometry Source Affect Results?
IP mass spectrometry is a technique that uses specific antibodies to identify and enrich specific protein complexes, and combines it with mass spectrometry analysis to identify the member proteins within the complex. This technique is widely used in biopharmaceutical research and disease studies, and careful consideration of the endogenous issues of the mass spectrometry source is necessary to obtain reliable results.
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• Quantitative Analysis of Proteins by Liquid Chromatography
Liquid chromatography quantitative analysis of proteins is one of the core techniques in modern biopharmaceutical research. It not only helps scientists understand protein expression levels and structures, but also has important implications in areas such as biopharmaceutical development and biomarker screening.
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• Advantages of Quantitative Proteomics Analysis in Applications
Proteomics, as an important technology in the field of biopharmaceuticals, can comprehensively analyze the composition and function of proteins in organisms. Quantitative proteomics analysis further expands the application scope of this technology, allowing scientists to quantify changes in protein abundance and reveal their important roles in biological processes and disease development.
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• Principle of Proteomics Data Quality Assessment
Proteomics is the large-scale study of proteins, including their expression, modifications, and interactions within cells, tissues, or organisms. With the rapid advancement of high-throughput mass spectrometry (MS) technologies, the pace of proteomics data generation has increased significantly. However, ensuring the accuracy and reliability of such vast datasets has become a critical concern in proteomics research.
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• Application of Proteome Bioinformatic Analysis in Biological Networks
Proteins are the core molecules responsible for the execution of functions in living organisms. Proteomics, which studies the comprehensive expression and functions of proteins within cells, tissues, and organisms, has become a frontier in life sciences. Proteome bioinformatic analysis, by integrating large-scale proteomics datasets, provides powerful tools for studying protein interactions and regulatory mechanisms in biological networks.
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• Workflow of Proteome Bioinformatic Analysis
Proteomics is the study of all proteins within a biological system, including their composition, structure, functions, and interactions. It plays a pivotal role in unveiling the dynamic changes and mechanisms within biological systems. Bioinformatic analysis is an essential component of proteomic research, enabling scientists to decipher protein expression, modifications, functions, and interaction networks through in-depth analysis of mass spectrometry data.
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