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Proteomics Databases



Metabolomics Databases

• • The Basic Process of Antibody Sequencing

  Antibody sequencing is a technique used to determine the amino acid sequence of specific antibody molecules in monoclonal or polyclonal antibodies. This provides crucial information for understanding the specificity, activity, structure, and affinity of antibodies with antigens, and is important for antibody engineering, vaccine development, disease diagnosis, and therapeutic research.

• • Guidelines for Protein Sequence Analysis Using the SMART Tool

  "SMART" (Simple Modular Architecture Research Tool) is an online tool used to identify and analyze domains and functional sites in protein sequences. The basic steps to perform protein sequence analysis using SMART are as follows.

• • Antibody Amino Acid Sequencing Basic Process

  Antibody amino acid sequencing is performed to determine the amino acid sequence of the heavy and light chains of an antibody. This is typically done to address issues related to antibody specificity, activity, structure, and affinity for the antigen. The process of antibody amino acid sequencing generally involves the following steps.

• • Protein Amino Acid Sequencing: Unveiling Key Traits in Protein

  Protein amino acid sequencing is the process of determining the sequence of amino acids in a protein molecule. This process is crucial for understanding the structure and function of proteins, as protein function is often closely related to its amino acid sequence.

• • Overview of Methods for Protein Amino Acid Sequence Detection

  Protein amino acid sequence detection is performed to determine the primary structure of proteins, which refers to the linear arrangement of amino acids, as they are the building blocks of proteins and arranged in a specific linear sequence. Understanding this primary structure is similar to deciphering the genetic code of proteins and it holds significant importance in various scientific disciplines.

• • Overview of Key Protein Structure Analysis Techniques

  Protein function is directly determined by its structure, interactions with other proteins, and its location within cells, tissues, and organs. Large-scale studies of protein structure and function in proteomics have made it possible to identify protein biomarkers associated with specific disease states and provide potential targets for treatment.

• • Antibody De Novo Sequencing: Revealing Amino Acid Sequences

  Antibody de novo sequencing refers to the process of deducing the amino acid sequence of an antibody and identifying any relevant post-translational modifications without prior knowledge of the DNA or protein sequence.The sequence information of antibodies is crucial for understanding the structural basis of antigen binding and enables antibodies to be used as therapeutic and research tools. Sequencing monoclonal antibodies aids in the development of biopharmaceuticals and diagnostic kits.

• • Proteome Sequencing Technology

  Protein sequencing is the process of determining the amino acid sequence of a protein, either in whole or in part. It determines the primary structure of the protein and influences its higher-order structure and function. The determination of protein amino acid sequence is fundamental to protein chemistry research. By analyzing the amino acid sequence of a protein, a wealth of information can be obtained and applied to other related fields, such as protein identification, design of molecular cloning probes.

• • Multiple Sequence Protein Homology Comparison Analysis

  Multiple sequence protein homology comparison analysis is a method used to compare the similarity and homology among multiple protein sequences. This analysis is commonly used for studying protein families, evolutionary relationships, and functional predictions.

• • Protein Primary Structure Determination Methods

  Protein molecules are biomacromolecules formed by the connection of many amino acids through peptide bonds. Proteins with physiological functions in the body have an ordered structure. Each protein has a specific amino acid composition percentage, amino acid sequence, and specific arrangement of peptide chains in space. Therefore, the protein structure composed of amino acid sequences and spatial arrangement of peptide chains is the structural basis for the unique physiological functions of each protein.