Resources

Proteomics Databases



Metabolomics Databases

• • Exploring Peptide Structure Identification: Mass Spectrometry

  Peptides are biopolymers composed of amino acids, and the identification of their higher-order structure is crucial for understanding their function and interactions. In the field of biopharmaceuticals, accurate determination of the higher-order structure of peptide drugs is required for their development and optimization.

• • SILAC-Based Co-IP-MS for High-Throughput Protein Interaction Analysis

  Protein-protein interactions (PPIs) are a crucial area of biological research, essential for understanding complex cellular processes. Studying how proteins interact with other molecules can reveal their roles in processes such as signal transduction, metabolism, and gene expression regulation.

• • Peptide Sequencing Applications: Breakthrough in Protein Structure Characterization

  Protein is one of the fundamental functional molecules in living organisms, and its structure is closely related to its function. Understanding the structure of proteins is of great significance for revealing their functions and studying related diseases. Peptide sequencing, as a key technique, provides a breakthrough for the characterization of protein structures.

• • SILAC-Based Protein-Protein Interaction Analysis Using Mass Spectrometry

  Protein-Protein Interactions (PPIs) are a critical area of biological research, essential for almost all cellular processes and functions. Understanding these interactions not only elucidates fundamental biological mechanisms but also identifies potential therapeutic targets for diseases. In recent years, mass spectrometry (MS)-based methods for analyzing PPIs have gained widespread use, particularly when combined with Stable Isotope Labeling by Amino acids in Cell culture (SILAC) technology.

• • Protein-Protein Interaction Analysis Using Co-IP Coupled with MS

  Protein-protein interactions (PPIs) are pivotal in cellular functions, influencing processes such as signal transduction, gene expression, and metabolism. Understanding these interactions is critical for unraveling the complexities of biological systems. Mass spectrometry (MS) has become a leading method for analyzing protein interactions due to its high sensitivity and ability to handle large-scale data.

• • In Vivo and In Vitro Crosslinking for Protein Interaction Detection

  Protein-protein interactions are fundamental to numerous physiological functions in living organisms. To gain deeper insights into these interactions, researchers have developed various experimental techniques aimed at elucidating the relationships between proteins. Among these techniques, in vivo and in vitro cross-linking have emerged as pivotal methods for investigating protein-protein interactions.

• • Analysis of Protein-Protein Interactions Using GST Pull-Down Assay

  Protein-protein interactions (PPIs) are fundamental to various biological processes, including cellular signaling, metabolic regulation, and structural maintenance. Investigating these interactions is crucial for understanding cellular functions and disease mechanisms. The GST Pull-Down Assay, a classical biochemical technique, is widely employed to study the physical interactions between proteins.

• • Quantitative Protein Interaction Analysis Based on SILAC Combined with Co-IP-MS

  Protein-protein interactions are pivotal in biological processes such as signal transduction, metabolic regulation, and gene expression. Understanding these interactions is crucial for revealing the molecular mechanisms of cellular functions and can also identify new therapeutic targets for disease treatment.

• • Quantitative Analysis of Proteomics Using Isotopic Labeling Methods

  Proteomics, the large-scale study of proteins, is a rapidly advancing field that holds the potential to unravel the complexities of biological systems. One crucial aspect of proteomics is quantitative analysis, which involves measuring the abundance of proteins in different biological samples.

• • Detection of Proteins Using SDS-PAGE

  SDS-PAGE (Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis) is a powerful technique for protein separation. It is widely used in biological research to analyze the composition of protein mixtures, determine the relative molecular mass of proteins, and isolate specific proteins for further study.