What Software Can Be Used to Analyze Circular Dichroism Results
Circular dichroism (CD) results can be analyzed using various software tools. Below are several widely adopted options:
1. CDPro
CDPro is a widely used software suite for circular dichroism data analysis, comprising three main algorithms: CONTIN, SELCON3, and CDSSTR. CONTIN and SELCON3 estimate protein secondary structure by comparing CD spectra against reference datasets derived from proteins of known structure, even in cases where the structure of the target protein is unknown. CDSSTR employs a parameter-fitting approach, predicting secondary structure by minimizing the root-mean-square deviation between the experimental and reference spectra.
2. DichroWeb
DichroWeb is an online platform for circular dichroism data analysis. It allows users to upload CD spectra and select from a range of analytical methods, including CONTIN, SELCON3, and VARSLC, to perform secondary structure estimations.
3. BESTSEL
BESTSEL is an online analytical tool that predicts protein secondary structure using an updated reference database of circular dichroism spectra. It provides enhanced accuracy in distinguishing various β-structure types.
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider.
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