Resources

Proteomics Databases



Metabolomics Databases

• • Analysis of Peptide Structure via LC-MS

  Peptides, as the building blocks of proteins, perform various biological functions and possess wide-ranging applications. Analyzing peptide molecular structures accurately is particularly crucial for biomedicine and basic research. Liquid chromatography-mass spectrometry (LC-MS) technology, with its high separation capacity and sensitivity, has become a core tool in peptide structure analysis.

• • Detection of Peptide Purity by RP-HPLC and Mass Spectrometry

  Peptides play a vital role in biomedical and chemical research, particularly in drug development and biomarker discovery. Accurate determination of peptide purity is essential to ensure therapeutic efficacy and safety. The combined use of reverse-phase high-performance liquid chromatography (RP-HPLC) and mass spectrometry (MS) is a commonly applied method in peptide purity analysis, providing high sensitivity and resolution.

• • Analysis of Peptide Purity via HPLC

  High-Performance Liquid Chromatography (HPLC) is a widely utilized analytical tool employed to assess peptide purity, crucial in fields such as drug development, synthetic chemistry, and proteomics. Precise evaluation of peptide purity is essential for understanding its functionality, characteristics, and potential applications.

• • Detection of Peptides Using HPLC

  High-performance liquid chromatography (HPLC) is an analytical technique widely used for separating, detecting, and quantifying compounds. In recent years, HPLC has been extensively applied in the detection and quantification of peptides, particularly due to its excellent performance in separating peptides within complex sample mixtures. Peptides, as fragments of proteins, are significant in various biological research and biopharmaceutical fields due to their structural diversity.

• • KEGG Pathway Enrichment Analysis Using KOBAS Software

  KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment analysis is a powerful bioinformatics tool extensively used in genomics and proteomics research to identify functional distributions within gene or protein sets. KOBAS software, known for its accuracy and efficiency in pathway annotation and enrichment, is a preferred tool for large-scale omics data analysis.   The KEGG database offers comprehensive information on biological pathways, including metabolic pathways, signaling cascades......

• • Comparative Analysis of Differential Protein Expression Using Proteomic Methods

  Proteins play a central role in biological systems, serving as essential components for structural and functional processes. Variations in the expression levels of specific proteins are closely associated with cellular physiological adjustments. By leveraging proteomic methods, researchers can systematically detect and quantify protein changes across various conditions, providing insights into underlying molecular mechanisms.   Proteomics investigates the composition, structure, function, and interact......

• • Detection of Protein Biomarkers Using Olink PEA

  Protein biomarkers refer to protein molecules that reflect specific states of an organism, playing a crucial role in early disease diagnosis, prognosis, and therapeutic monitoring. With the rapid advancement of proteomics technologies, research on protein biomarkers has garnered significant attention.

• • Procedure for Target Identification in Chemical Proteomics

  Chemical proteomics is an interdisciplinary field that combines chemical tools with proteomics methods to study the interactions between chemical compounds and proteins. Through chemical proteomics, researchers can identify potential protein targets that interact with specific compounds in biological samples. This approach has wide applications in drug discovery, new drug development, and biomarker identification.

• • Analysis of Chemical Proteomics Using Activity-Based Probes

  Chemical proteomics is a research field aimed at uncovering the functions, activities, and roles of proteins in biological processes. As proteomic technologies have evolved, activity-based protein profiling (ABPP) has emerged as a powerful tool for studying the activity states of proteins and mechanisms of drug action. ABPP employs chemical probes that selectively bind to specific active sites on proteins, allowing for the targeted labeling, enrichment, and identification of active proteins.

• • Chemical Proteomics Analysis Using the DARTS Method

  Chemical proteomics is a crucial technology for studying the interactions between small molecules and proteins. It provides key scientific insights for drug discovery, target validation, and biomarker research. Among various chemical proteomics approaches, DARTS (Drug Affinity Responsive Target Stability) is an efficient and label-free method widely used for exploring the interactions between compounds and protein targets.