Resources

• • Exploring New Avenues and Approaches for Protein Structure Decoding

  Protein structure analysis is a key method to study the three-dimensional conformations and interaction modes of proteins.    New Approaches 1. The application of Artificial Intelligence (AI) in Protein Structure Analysis AI technology has brought new breakthroughs in protein structure analysis. By training neural networks and deep learning algorithms, scientists can use a large amount of structural data for prediction and modeling, thus inferring the structure and function of unknown proteins. This m......

• • Decrypting Protein Structure: Exploring the Intricate Design of Biological Systems

  Protein Structure can be divided into four levels: primary structure (amino acid sequence), secondary structure (α-helix and β-sheet), tertiary structure (spatial folding), and quaternary structure (combination of multiple polypeptide chains).   Methods of Deciphering Protein Structure To decipher the structure of proteins, scientists have developed many experimental and computational methods. X-ray crystallography, nuclear magnetic resonance, and electron microscopy are common experimental methods th......

• • Using Proteomics to Open a New Era in Biomedical Research

  In recent years, proteomics technology, with its high efficiency, high sensitivity, and high resolution, has become an important tool in biomedical research. Using proteomic technology, scientists have been able to delve deeper into the composition, structure, and function of proteins, thereby ushering in a new era of biomedical research.   Principle of Proteomic Technology Proteomic technology is based on the principle of mass spectrometry, by analyzing the proteins in a sample, it reveals informatio......

• • Advances in Phospho Proteomics for Disease Research

  Phospho proteomics aims to uncover the complex mechanisms of intracellular signal transduction through large-scale analysis of phosphorylated proteins. This approach integrates mass spectrometry with proteomics techniques, enabling the precise identification and quantification of phosphorylation sites on proteins. This helps researchers understand how cells regulate various physiological and pathological processes through phosphorylation. As a key post-translational modification, phosphorylation plays......

• • Advancements in Protein Sequencing Technique

  Protein sequencing is a critical technique for determining the amino acid sequence and modification states of proteins, and it plays a pivotal role in life sciences research, drug development, and disease diagnostics. By employing protein sequencing, researchers gain deeper insights into the structure, function, and biological mechanisms of proteins within organisms, providing an essential tool for decoding the molecular underpinnings of life.   The main objective of protein sequencing is to identify ......

• • Molecular Weight Analysis: Methods and Applications in Science

  Molecular weight analysis is a fundamental technique in chemistry and biology, enabling the determination of molecular weights and providing essential insights into molecular structures and compositions. By analyzing molecular weight, researchers can investigate the properties of complex compounds, supporting advancements in drug development, materials science, and environmental studies. Key methods for molecular weight analysis include mass spectrometry, gel permeation chromatography, and ultracentri......

• • Advancements in Protein Mass Measurement Techniques

  Proteins are macromolecules composed of amino acids linked by peptide bonds, with molecular mass variations depending on their sequence and number of amino acids. The core objective of protein mass measurement is to precisely determine the mass of these biomolecules, enabling detailed insights into their structural and functional properties. This process relies on mass spectrometry, where samples are ionized to produce charged ions for analysis. By measuring the mass-to-charge ratio (m/z) of these ion......

• • Exploring the Potential Applications of Protein Structure Analysis in the Field of Biomedicine

  With the advancement of scientific technology, the potential application of protein structure analysis in the field of biomedicine is gradually revealed.   Techniques for Protein Structure Analysis 1. X-ray Crystallography X-ray Crystallography is one of the most commonly used methods for protein structure analysis. By the X-ray diffraction patterns of protein crystals, scientists can determine the atomic structure of proteins, thereby revealing its functions and modes of interaction.   2. Nuclear Mag......

• • Comparison Analysis of Protein Molecular Weight by Mass Spectrometry Detection under Reduced and Non-Reduced Conditions

  Protein molecular weight is one of the important indicators to understand the structure and characteristics of proteins. Mass spectrometry technology plays an important role in protein analysis, including commonly used mass spectrometry detection methods such as Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) and Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). In the process of protein mass spectrometry detection, sample processing and analysis me......

• • Exploring the Mystery of Protein Denaturation: Characterization Methods and Technological Analysis

  Protein denaturation is one of the important regulatory mechanisms of protein structure and function. Through the characterization methods and techniques of protein denaturation, we can understand the changes and stability of protein structure and reveal the mysteries of protein structure. This is of great significance for drug development, protein engineering, and understanding protein function.   Causes and Types of Protein Denaturation 1. Causes of Protein Denaturation Protein denaturation can be c......