Resources

• • Application of O-Glycan Profiling

  O-glycans are a crucial type of carbohydrate involved in various biological processes, including cell signaling, protein functionality, and stability. Therefore, the analysis of O-glycans is vital for biological research and medical diagnostics.

• • Workflow of O-Glycan Profiling

  O-glycans are polysaccharides formed by the attachment of sugar molecules to proteins or lipids via oxygen bonds. They are widely present in biological systems and play critical roles in biological functions and disease mechanisms. Analyzing O-glycans is essential for understanding their involvement in cellular signaling, immune responses, and cell recognition.

• • Principle of O-Glycan Profiling

  O-glycans are carbohydrate modifications of proteins or peptides, formed through linkage to the hydroxyl groups of serine or threonine residues. These modifications play significant roles in physiological functions, including signal transduction, intercellular interactions, and immune responses. Therefore, the analysis of O-glycans is vital for understanding their functions in biological processes.

• • Amino Acid Chirality Analysis of Peptide Drugs (LC-MS)

  Peptide drugs are biologically active molecules composed of multiple amino acids linked by peptide bonds. Typically, they consist of 10 to 100 amino acids with a molecular weight below 10,000. Peptide drugs are mostly derived from endogenous or natural peptides, thus they have little or no side effects on the human body. Compared to protein-based drugs, peptide drugs have advantages such as good stability, high purity, low production costs, and low immunogenicity.

• • Mass Spectrometry for Molecular Weight: Common Methods and Applications

  Mass spectrometry molecular weight determination is one of the commonly used analytical techniques in the field of biopharmaceutical research. By measuring the mass of molecules, scientists can understand the structure and properties of molecules, thereby advancing drug development and biological research.

• • Exploring Peptide Mapping Analysis: Unraveling Protein Composition Diversity

  Peptide mapping analysis is a method used to analyze the diversity of protein composition. This article will provide a detailed introduction to the principles and applications of peptide mapping analysis. Protein Composition Diversity Proteins are composed of amino acids, and the types and sequences of amino acids determine the structure and function of proteins. In living organisms, the same protein may exist in multiple different forms, which is known as protein composition diversity.

• • Protein Interaction Analysis by Mass Spectrometry

  Protein-protein interaction mass spectrometry analysis is an important technique for studying the interactions between proteins. It utilizes mass spectrometry to determine the structure and properties of protein molecules by measuring their mass and charge. Protein-protein interaction mass spectrometry analysis, on the other hand, involves analyzing the interactions between proteins to uncover their functions and regulatory mechanisms within cells.

• • How to Apply Chemical Proteomics for Sample Analysis?

  Chemical proteomics is a proteomics technique that studies all proteins within an organism. Proteins are one of the most important molecules in living organisms and play various roles, such as catalyzing reactions, transmitting signals, and providing structural support. The goal of chemical proteomics is to understand the role of proteins in biological processes, particularly their critical role in disease occurrence and treatment.

• • Proteomics Sample Quantification Techniques: IP-MS Database Applications

  Proteomics is an important means to study the composition and function of proteins in organisms. In proteomic research, the choice of sample size is one of the crucial factors.

• • Understanding Proteomics Charts: A Comprehensive Guide to Mass Spectra

  Proteomics is the scientific field that studies the composition, structure, and function of all proteins in an organism. Through mass spectrometry technology, we can obtain a large amount of proteomic data, with the most common being proteomic graphs. However, understanding and interpreting proteomic graph results may be challenging for non-professionals.