Resources

• • Advancements in Protein Mass Measurement: Techniques and Applications

  Proteins are macromolecules composed of amino acids linked by peptide bonds, with molecular mass variations depending on their sequence and number of amino acids. The core objective of protein mass measurement is to precisely determine the mass of these biomolecules, enabling detailed insights into their structural and functional properties. This process relies on mass spectrometry, where samples are ionized to produce charged ions for analysis. By measuring the mass-to-charge ratio (m/z) of these ion......

• • Protein Interaction Mass Spectrometry: A Cutting-Edge Tool for Functional Proteomics

  Overview of Proteomic Technology for Protein Interactions The proteomic technology for protein interactions is a technology that uses mass spectrometry to study the interactions between proteins. It can identify and analyze the interactions between proteins using various experimental strategies, such as affinity chromatography, co-precipitation, and yeast two-hybrid, combined with mass spectrometry.   Importance of Proteomic Technology for Protein Interactions The proteomic technology for protein inte......

• • Protein Mass Spectrometry: Elucidating Molecular Complexity in Biological Systems

  Overview of Protein Mass Spectrometry Technology Protein mass spectrometry technology is a method for obtaining information by analyzing the mass and relative abundance of protein molecules in protein samples. It is based on mass spectrometry instruments, through mass analysis and the detection of molecular ions, to identify and analyze the protein composition and characteristics in protein samples.   Importance of Protein Mass Spectrometry Analysis Protein mass spectrometry analysis is of great signi......

• • Using Protein Mass Spectrometry to Reveal Metabolic Pathways and Regulatory Networks

  Protein mass spectrometry is a robust quantitative approach leveraging mass spectrometry to study proteins. By separating proteins, digesting them into peptides, and analyzing these peptides quantitatively, this technique provides a comprehensive understanding of protein composition and function. Common quantitative strategies include intensity-based, isotope-labeling, and computational quantification, all of which depend on meticulous sample preparation and precise mass spectrometric workflows.   Ins......

• • Exploring New Avenues and Approaches for Protein Structure Decoding

  Protein structure analysis is a key method to study the three-dimensional conformations and interaction modes of proteins.    New Approaches 1. The application of Artificial Intelligence (AI) in Protein Structure Analysis AI technology has brought new breakthroughs in protein structure analysis. By training neural networks and deep learning algorithms, scientists can use a large amount of structural data for prediction and modeling, thus inferring the structure and function of unknown proteins. This m......

• • Decrypting Protein Structure: Exploring the Intricate Design of Biological Systems

  Protein Structure can be divided into four levels: primary structure (amino acid sequence), secondary structure (α-helix and β-sheet), tertiary structure (spatial folding), and quaternary structure (combination of multiple polypeptide chains).   Methods of Deciphering Protein Structure To decipher the structure of proteins, scientists have developed many experimental and computational methods. X-ray crystallography, nuclear magnetic resonance, and electron microscopy are common experimental methods th......

• • Using Proteomics to Open a New Era in Biomedical Research

  In recent years, proteomics technology, with its high efficiency, high sensitivity, and high resolution, has become an important tool in biomedical research. Using proteomic technology, scientists have been able to delve deeper into the composition, structure, and function of proteins, thereby ushering in a new era of biomedical research.   Principle of Proteomic Technology Proteomic technology is based on the principle of mass spectrometry, by analyzing the proteins in a sample, it reveals informatio......

• • Advances in Phospho Proteomics for Disease Research

  Phospho proteomics aims to uncover the complex mechanisms of intracellular signal transduction through large-scale analysis of phosphorylated proteins. This approach integrates mass spectrometry with proteomics techniques, enabling the precise identification and quantification of phosphorylation sites on proteins. This helps researchers understand how cells regulate various physiological and pathological processes through phosphorylation. As a key post-translational modification, phosphorylation plays......

• • Advancements in Protein Sequencing Technique

  Protein sequencing is a critical technique for determining the amino acid sequence and modification states of proteins, and it plays a pivotal role in life sciences research, drug development, and disease diagnostics. By employing protein sequencing, researchers gain deeper insights into the structure, function, and biological mechanisms of proteins within organisms, providing an essential tool for decoding the molecular underpinnings of life.   The main objective of protein sequencing is to identify ......

• • Molecular Weight Analysis: Methods and Applications in Science

  Molecular weight analysis is a fundamental technique in chemistry and biology, enabling the determination of molecular weights and providing essential insights into molecular structures and compositions. By analyzing molecular weight, researchers can investigate the properties of complex compounds, supporting advancements in drug development, materials science, and environmental studies. Key methods for molecular weight analysis include mass spectrometry, gel permeation chromatography, and ultracentri......