Resources

Proteomics Databases



Metabolomics Databases

• • Application of GO Functional Annotation and Enrichment Analysis

  Gene Ontology (GO) serves as a foundational tool in bioinformatics, providing researchers with a systematic framework for describing the functions of genes and their products. GO functional annotation classifies gene products into three dimensions: Biological Process (BP), Cellular Component (CC), and Molecular Function (MF), facilitating a deeper understanding of gene roles within cellular activities.

• • Principle of GO Functional Annotation and Enrichment Analysis

  Gene Ontology (GO) is a critical tool in biological research for describing the functions of genes and gene products. With the advancement of high-throughput sequencing technologies, researchers are faced with vast amounts of genetic data. GO functional annotation and enrichment analysis have become essential methods for revealing gene functions, elucidating biological processes, and predicting gene regulatory networks.

• • Advantages and Limitations of GO Functional Annotation and Enrichment Analysis

  Gene Ontology (GO) provides a standardized vocabulary for describing gene and protein functions, structured around three main domains: Biological Process (BP), Molecular Function (MF), and Cellular Component (CC). In bioinformatics analyses, GO functional annotation and enrichment analysis serve as crucial tools for understanding genomic data, enabling researchers to uncover the potential biological functions of genes and proteins.

• • Bioinformatics Interpretation of the Primary Structure of Antibody Drugs

  The primary structure of an antibody, that is, its amino acid sequence, contains a wealth of information. Bioinformatics, as an interdisciplinary field, provides us with powerful tools and techniques for interpreting the primary structure of antibody drugs. This article will focus on the application of bioinformatics in the primary structure of antibody drugs, and discuss its importance in sequence analysis, structure prediction, and function prediction.

• • Parallel Reaction Monitoring (PRM) Method in Protein Post-Translational Modificationomics

  Proteomic Post-Translational Modification (PTM) is a branch of science that studies the overall status and dynamic changes of protein post-translational modifications. It involves various types of PTM, such as phosphorylation, acetylation, SUMOylation, ubiquitination, methylation, etc. To efficiently and accurately detect and quantify the PTM status of proteins, mass spectrometry techniques, particularly targeted spectrometry methods like Parallel Reaction Monitoring (PRM), have been widely utilized.

• • Mass Spectrometry Detection of Protein Molecular Mass

  In the field of scientific research, mass spectrometry technology plays a key role in detecting the mass and structure of proteins. Compared to other protein detection methods, this technology can provide more direct and accurate results, which is why it is highly favored by researchers.   Simply put, mass spectrometry detection is the process of providing a substance with enough energy to ionize it, producing atoms or molecules with positive and negative charges.

• • Protein Primary Structure Determination

  Protein structures can be divided into four levels: primary, secondary, tertiary, and quaternary structure. The primary structure of a protein refers to the linear sequence composed of amino acids. Each amino acid is connected by a peptide bond to form a polypeptide chain. The primary structure of a protein determines the formation of its secondary, tertiary, and quaternary structures, which in turn determines the functions and interactions of the protein.

• • Protein Ubiquitination Sites Identification by Mass Spectrometry

  Ubiquitination modification is an important post-transcriptional modification of proteins in living organisms, with profound effects on many physiological processes such as gene expression, cell cycle regulation, and immune responses. However, the accurate identification of ubiquitination sites and their specific biological significance is one of the frontier challenges in the field of biopharmaceuticals.

• • Quantitative Proteomics in Cancer Research

  Cancer, as a serious disease, significantly affects human health and quality of life. Early diagnosis and effective treatment of cancer are crucial for improving patient survival rates. In recent years, quantitative proteomics, as a powerful technique, has played an important role in cancer research. We will explore the use of quantitative proteomics in cancer research, focusing on its potential to identify biomarkers and therapeutic targets.

• • Comprehensive Analysis of Protein-Protein Interaction Verification Methods

  MtoZ Biolabs is your optimum choice for protein-protein interactions services, with high-quality and efficient solutions.   Proteins are among the most significant molecules in living organisms, playing various key roles within cells and controlling physiological processes within the organism. Furthermore, interactions between proteins, also known as protein-protein interactions, form the basis of cellular function networks.