Resources
Proteomics Databases
Metabolomics Databases
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• Application of MS Based Protein Identification
Mass spectrometry (MS) is a powerful and highly sensitive analytical tool widely used in proteomics research. Mass spectrometry-based protein identification (MSPI), a critical branch of MS technology, has become one of the core techniques in modern biological research. This article will detail the basic principles of MSPI and its applications in various fields.
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• Advantages and Disadvantages of Protein Molecular Weight Determi
The molecular weight of a protein is the sum of the relative atomic masses of all the atoms in its chemical formula. Accurate determination of protein molecular weight is essential for structural analysis, functional studies, and biopharmaceutical development. Commonly used methods include viscosity measurements, gel permeation chromatography (GPC), SDS-PAGE, light scattering, and mass spectrometry (MS).
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• Workflow of MS Based Protein Identification
Mass spectrometry-based protein identification is a sophisticated and precise method used to identify and quantify proteins in a sample. By leveraging mass spectrometry technology, researchers can gain deep insights into the structural and functional properties of proteins, thus elucidating the dynamic changes in biological systems.
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• Advantages and Disadvantages of MS Based Protein Identification
Mass spectrometry (MS) has become a cornerstone in proteomics research, providing invaluable data on the mass and structure of proteins.
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• Principle of MS Based Protein Identification
Mass spectrometry (MS) is a powerful analytical technique widely used in proteomics for identifying and quantifying proteins. The process of MS protein identification involves several critical steps: sample preparation, mass spectrometric analysis, data processing, and result interpretation. This article details the core principles underlying MS protein identification.
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• Principle of Protein Molecular Weight Determination
Protein molecular weight is the sum of the relative atomic masses of all the atoms in a protein's chemical formula. It is a primary parameter for identifying peptides and proteins and assessing the accuracy of their structures. Several techniques are available for determining protein molecular weight, each based on different principles and offering unique advantages.
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• TMT Based Proteomics Service
In the world of biological sciences, the study of proteins holds paramount importance. Proteins are the workhorses of cells, playing crucial roles in almost all biological processes. Understanding these proteins, their functions, and interactions is essential for advancing our knowledge in health, disease, and overall biological function. One of the cutting-edge techniques propelling this field forward is Tandem Mass Tag (TMT) based proteomics.
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• Quantitative Proteomics Services
Quantitative proteomics is a rapidly evolving field that offers comprehensive insights into protein expression, modification, and interaction within biological systems. By leveraging advanced mass spectrometry techniques, quantitative proteomics services enable the precise measurement of protein abundances, providing critical data for various applications, from basic research to clinical diagnostics.
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• Proteomics Services and Quantitative Proteomics
Proteomics, the large-scale study of proteins, is a critical field in molecular biology. Proteins, being the functional molecules in cells, play essential roles in virtually all biological processes. The term 'proteomics' draws an analogy with genomics, the study of genes. Unlike the static nature of the genome, the proteome is highly dynamic and varies with time and distinct requirements or stresses that a cell or organism undergoes.
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• Mechanism of Accurate Mass Determination
In modern biological research, mechanisms for accurate mass determination are crucial. Whether studying protein structures and functions or elucidating complex metabolic pathways, precise mass measurement provides vital data support. This article will focus on the fundamental principles, commonly used techniques, and applications of accurate mass determination in biology.
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