Resources

Proteomics Databases



Metabolomics Databases

• • Principle of Protein Identification by Tandem MS

  Protein tandem mass spectrometry (MS/MS) is a highly precise and sensitive technique widely used in proteomics research. The principle involves using a mass spectrometer to measure the mass-to-charge ratio (m/z) of peptides, which allows for the inference of the protein's sequence and structure. The following section details the principles of protein tandem mass spectrometry identification.

• • Mechanism of Protein Characterization Analysis

  Proteins are some of the most vital molecules in biological systems, executing nearly all biological functions. From enzymes that catalyze chemical reactions to carriers that transport molecules and scaffold proteins that form cellular structures, proteins play indispensable roles in living organisms. To understand the functions of proteins, scientists need to perform comprehensive characterization analysis.

• • Application of Protein Characterization Analysis

  Proteins are among the most important functional molecules in living organisms, involved in nearly all biological processes. The study of protein structure and function holds a significant place in biology and medicine, and protein characterization analysis is a fundamental method for understanding proteins. This analysis involves a series of techniques and methods to comprehensively analyze and characterize the structure, function, interactions, and expression of proteins.

• • Workflow of Protein Characterization Analysis

  Protein characterization analysis is a crucial step in biological research, providing detailed insights into the structure, function, and interactions of proteins. The workflow of protein characterization analysis includes sample preparation, separation and purification, mass spectrometry analysis, data processing, and functional validation.

• • Principle of Protein Characterization Analysis

  Protein characterization analysis plays a crucial role in biological research. By analyzing protein structure, function, dynamics, and interactions, we can uncover fundamental principles of biological processes and provide scientific evidence for disease treatment and drug development. This article systematically introduces the principles of protein characterization analysis in three main aspects: protein separation, identification, and functional analysis.

• • MS-Based Accurate Mass Determination Procedure

  Mass spectrometry (MS) is a highly sensitive and high-resolution analytical technique widely used in biological research. The Mass Spectrometry-based Accurate Mass Measurement (MS-AMM) technique determines the precise mass of molecular ions to infer their chemical composition and molecular structure, establishing itself as a core tool in modern biochemistry and molecular biology research.

• • Principle of Unknown Protein Identification

  Proteins play fundamental roles in life activities, with their diverse functions and structures underpinning various biological processes. Despite advances in proteomics, many proteins remain poorly understood. To address this, scientists employ a range of techniques to analyze these unknown proteins.

• • Application of Protein Molecular Weight Determination

  Proteins are the workhorses of biological systems, playing critical roles in virtually every cellular process. Understanding the molecular weight of proteins is fundamental to biochemistry and molecular biology, providing insights into their structure, function, and interactions. This article explores the importance, methodologies, and applications of protein molecular weight determination, blending scientific rigor with accessible explanations.

• • Mechanism of MS Based Protein Identification

  Mass spectrometry (MS) is a powerful analytical tool widely used in biological research. MS technology is essential for protein identification and quantification due to its high sensitivity, accuracy, and resolution. This article explores the mechanisms of mass spectrometry-based protein identification and introduces the latest advancements in this field.

• • Workflow of Protein Molecular Weight Determination by MS

  Proteins, the workhorses of the cell, play crucial roles in virtually all biological processes. Understanding their molecular weight is fundamental in characterizing their structure and function. Mass spectrometry (MS) has emerged as a pivotal tool in this regard, offering unmatched sensitivity and accuracy. This article outlines the standard workflow for determining protein molecular weight using MS, bridging the gap between complex scientific methodology and comprehensible exposition.