Resources
Proteomics Databases
Metabolomics Databases
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Protein biomarker discovery aims to provide vital tools for disease diagnosis, treatment, and prognosis by identifying and validating changes in protein profiles under specific biological conditions. Protein biomarkers are molecular indicators in organisms that reflect physiological or pathological states. These biomarkers are invaluable in biomedical research as they facilitate early disease detection, disease progression assessment, treatment monitoring, and the development of novel therapeutic stra......
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• Protein Ligand Interaction Profile
Protein ligand interaction profile is a critical approach for studying the relationships between proteins and their interacting molecules in biological systems. This analysis is focused on understanding the interaction processes between proteins and their ligands, which can include small molecules, ions, and biomacromolecules such as drug compounds, metabolites, and nucleic acids. These interactions are crucial in regulating biological processes, including signal transduction, metabolic control, and g......
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LC-MS amino acid analysis is a powerful analytical method that integrates liquid chromatography (LC) and mass spectrometry (MS) to accurately identify and quantify amino acids in samples. The technique combines LC's ability to separate complex sample components with MS's capability to detect and quantify these components, resulting in high sensitivity, resolution, and versatility. This makes LC-MS amino acid analysis especially effective for examining complex samples with low amino acid concentrations......
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• Western Blotting Quantitative
Western Blotting Quantitative is a widely used technique for detecting and quantifying the expression levels of specific proteins in complex biological samples. This method integrates electrophoretic separation, membrane transfer, and antibody-based detection to deliver precise quantitative insights into target protein expression. The standard workflow involves separating proteins via polyacrylamide gel electrophoresis, transferring them onto nitrocellulose or polyvinylidene fluoride (PVDF) membranes,......
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• Data-Independent Acquisition
Data-Independent Acquisition (DIA) is a valuable technique for quantitative proteomics analysis in complex biological samples. Unlike traditional Data Dependent Acquisition (DDA), which selectively fragments specific precursor ions and may overlook low-abundance proteins, Data-Independent Acquisition simultaneously captures all precursor ions and their fragments in a single experiment. This approach provides comprehensive and reproducible proteomic data, supporting biomedical research, drug developmen......
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• Advances in Antibody Characterization Techniques
Antibody characterization techniques encompass a comprehensive set of modern bioanalytical methods designed to systematically analyze and characterize the sequence, structure, modifications, affinity, and functional properties of antibody molecules. As essential components of the immune system, antibodies play an irreplaceable role in fundamental research, disease diagnostics, and the development of therapeutic antibody drugs. With the rapid advancement of biopharmaceutical technologies, innovative th......
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• Antibody Characterization Methods
Antibody Characterization Methods encompass a range of experimental and analytical techniques designed to determine the specificity, affinity, and functional properties of antibodies. These methods are essential not only for basic scientific research but also for disease diagnostics, therapeutic antibody development, and biomarker discovery. Antibodies exert their biological effects through specific interactions with target antigens; however, rigorously validating antibody specificity and functionalit......
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Antibody sequence analysis is a method used to comprehensively determine and characterize the amino acid sequences of antibody molecules through advanced biotechnological approaches. Antibodies, as protein molecules produced by the immune system, specifically recognize and bind to antigens, playing a critical role in immune defense mechanisms. In biomedical research, drug development, and disease diagnostics, antibodies are indispensable tools. However, the structural complexity and diversity of antib......
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• Antibody Characterization Techniques
Antibody characterization techniques encompass a comprehensive set of modern bioanalytical methods designed to systematically analyze and characterize the sequence, structure, modifications, affinity, and functional properties of antibody molecules. As essential components of the immune system, antibodies play an irreplaceable role in fundamental research, disease diagnostics, and the development of therapeutic antibody drugs. With the rapid advancement of biopharmaceutical technologies, innovative th......
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mRNA HPLC analysis is a precise analytical method for separating, identifying, and quantifying mRNA samples. By combining the separation efficiency of high-performance liquid chromatography (HPLC) with advanced detection techniques, this method provides detailed insights into the molecular structure and purity of mRNA. In response to the rapid growth of mRNA-based technologies, HPLC analysis has become an indispensable tool in quality control for mRNA drug development, vaccine research, and gene thera......
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