Resources
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With the advancement of technology, the De Novo sequencing of antibody protein allows us to accurately obtain the protein sequence information of antibodies, enabling in-depth study of their functions and their relationship with diseases.
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• Key Technologies in Protein Identification and Sequence Analysis
Protein identification and sequence analysis are crucial for understanding cellular processes, disease mechanisms, and biopharmaceutical development.
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MtoZ Biolabs utilize GST Pull-Down kits, paired with a high-sensitivity UPLC-MS platform, to offer the most optimized one-stop solution for pull-down based protein analysis service. MS not only offers high sensitivity and specificity but also allows for the accurate identification of low-abundance and complex protein interaction networks. By applying MS to identify the proteins captured in the pull-down assay, it provides precise molecular-level information in a high-throughput context.
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• MtoZ Biolabs Offers Advanced Protein Post-Translational Modification Analysis Services
MtoZ Biolabs' protein post-translational modification analysis services cover a broad spectrum of modifications—including phosphorylation, ubiquitination, glycosylation, and more—that are critical in regulating protein function and cellular processes. Utilizing advanced mass spectrometry platforms like the Thermo Fisher Q Exactive HF and Orbitrap Fusion Lumos, combined with high-sensitivity nano-liquid chromatography (Nano-LC), we provide high-resolution detection of low-abundance modified peptides for.....
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• Protein Molecular Weight Determination Service at MtoZ Biolabs
Molecular weight determination of proteins is a critical step in protein characterization, playing a pivotal role across various fields such as biotechnology and biomedical research. It aids in understanding the structure, integrity, and authenticity of proteins, which is essential for advancing basic research and ensuring stringent quality control in biopharmaceutical production.
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• De Novo Sequencing of Peptides Innovating the Analysis Strategy of Peptide Quality Research
Peptide sequencing is an important strategy to accurately obtain the amino acid sequence of a peptide, which is a crucial component of protein molecules and possesses diverse biological functions and potential applications. Peptide sequencing from scratch is a powerful analytical approach that can bring new breakthroughs and advancements to peptide research.
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• Principles and Applications of Antibody Variable Region Classification
The variable region of antibodies is the key region that determines their diversity. This article will focus on the principles and applications of antibody variable region partitioning, explore innovative diversity analysis strategies, and emphasize its importance in biomedical research.
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The sequence features of the antigen-antibody binding site are closely related to their biological activity. Therefore, analyzing the binding site through antigen-antibody sequence analysis can explore the mechanism of antigen-antibody interaction and its association with biological activity.
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• Determination Methods and Prospects of Polypeptide Sequencing
Peptide chains are biopolymer molecules composed of amino acid residues connected by peptide bonds. The sequence of a peptide chain determines its structure and function. Accurate determination of the peptide chain sequence is crucial for research and development of biopharmaceuticals.
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• Absolute and Relative Quantitative Proteomics Analysis
Absolute quantification and relative quantification techniques are two major quantitative methods in proteomics, revealing abundance variations and functional characteristics of protein groups within an organism.
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