Resources
Proteomics Databases
Metabolomics Databases
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ICP Elemental Analysis is a highly precise analytical technique used for both qualitative and quantitative analysis of metallic and other elemental contents. The method involves introducing a sample into a high-temperature plasma, where elements are excited to emit light at characteristic wavelengths. The intensity of this light is measured by a spectrometer, allowing for the determination of the elemental composition within the sample. Owing to its high sensitivity, accuracy, broad detection range, a......
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Protein enrichment analysis is a bioinformatics approach designed to identify protein groups associated with specific biological processes, diseases, or experimental conditions from extensive proteomic datasets. By systematically screening and analyzing large-scale protein data, enrichment analysis highlights protein sets that demonstrate significant changes under defined conditions. This approach provides critical insights into protein functionality and dysregulation mechanisms, playing a pivotal rol......
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Comparative proteomics is a research methodology designed to identify differences and underlying mechanisms in protein composition, expression levels, modification states, and functional characteristics across diverse biological samples under distinct physiological or pathological conditions. The primary goal is to systematically compare proteins among multiple samples or experimental groups, generating critical data to elucidate biological processes. Unlike genomics or transcriptomics, proteomics pro......
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• Single Cell Protein Analysis
Single cell protein analysis is a transformative technology that enables the detection and quantification of intracellular protein composition and dynamic changes at single-cell resolution. Compared to traditional bulk proteomics methods, this approach offers significantly enhanced sensitivity and resolution, allowing researchers to study cellular heterogeneity and functional characteristics in unprecedented detail. In multicellular organisms, individual cells exhibit substantial diversity influenced ......
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• Protein Characterization Assays
Protein characterization assays are critical analytical techniques used to investigate the structure, function, and interactions of proteins. Proteins, as central molecules in cellular processes, perform diverse biological functions, including catalyzing biochemical reactions, transmitting cellular signals, and maintaining structural integrity. Through detailed analysis of the physical and chemical properties of proteins, these assays can provide insights into three-dimensional structures, post-transl......
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mAb characterization involves the comprehensive analysis and evaluation of the structure, function, and purity of monoclonal antibodies. In biotechnology and pharmaceutical development, mAbs are highly valued for their exceptional specificity and broad applications in disease diagnosis and therapy. Characterization aims to ensure the stability, efficacy, and safety of these biomolecules across development, production, and clinical use. Key aspects of mAb characterization include amino acid sequence ve......
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Protein pathway analysis is a fundamental technique in bioinformatics and systems biology, aimed at elucidating complex biological processes and functional mechanisms by studying proteins and their interaction networks. At its core, the analysis focuses on identifying and interpreting protein-protein interactions, offering insights into cellular functions, signaling pathways, metabolic networks, and disease mechanisms. By constructing protein interaction maps, researchers can identify functional modul......
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• HCP Analysis by Mass Spectrometry
In the biopharmaceutical industry, host cell proteins (HCPs) refer to residual contaminant proteins derived from host cells during the production process. These proteins can co-purify with therapeutic products, posing potential risks to the safety and efficacy of the final product. Therefore, rigorous detection and control of HCPs are essential. HCP analysis by mass spectrometry is a highly sensitive and reliable approach for identifying and quantifying these contaminants, ensuring product purity and ......
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• Advances in HPLC Protein Analysis
HPLC protein analysis is a key technique in proteomics research, widely employed for protein separation and characterization. The method relies on using a liquid mobile phase under high pressure to flow through a chromatographic column containing a stationary phase, enabling the separation of components in a protein mixture. Given the complexity and diversity of proteins, HPLC protein analysis plays an essential role in evaluating protein purity, identifying protein modifications, quantifying protein ......
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Proteomics sequencing is an advanced analytical technology designed to comprehensively study the entire protein complement of an organism, playing a central role in understanding biological processes. Proteins function as molecular machines, executing essential tasks such as maintaining cellular structures, catalyzing biochemical reactions, and regulating physiological processes. Following the completion of the Human Genome Project, scientists recognized that decoding the genome-wide expression of gen......
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