Resources
Proteomics Databases
Metabolomics Databases
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LC-MS/MS service integrates liquid chromatography and mass spectrometry for precise compound separation and molecular analysis. This methodology is extensively applied in proteomics, metabolomics, and pharmaceutical research within the life sciences. By leveraging liquid chromatography, the LC-MS/MS service effectively resolves compounds in complex biological samples, while tandem mass spectrometry provides high sensitivity and resolution for both qualitative and quantitative molecular assessments. Th......
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Pharmacokinetics analysis studies how drugs move through and are processed by the body, focusing on absorption, distribution, metabolism, and excretion. This type of analysis helps us understand how drug concentrations change over time within the body, allowing us to predict their behavior and inform clinical practices. Widely used in drug development, clinical trials, and personalized medicine, pharmacokinetics analysis supports researchers in determining optimal dosages and administration strategies......
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• Affinity Selection Mass Spectrometry
Affinity selection mass spectrometry (ASMS) is a sophisticated analytical technique that integrates affinity chromatography with mass spectrometry to identify and quantitatively evaluate interactions between biomolecules. Affinity Selection Mass Spectrometry employs specific affinity ligands-such as antibodies, peptides, or small molecules-to selectively capture target proteins or other biomolecules, followed by their identification using mass spectrometric analysis. This technique is pivotal in drug ......
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• Post-Translational Modification Mass Spectrometry
Post-Translational Modification Mass Spectrometry is a highly sensitive and precise technique used to identify and quantify modifications in proteins. Post-Translational Modification occur at specific sites after protein synthesis, through enzymatic or non-enzymatic reactions, and include modifications such as phosphorylation, acetylation, methylation, glycosylation, and ubiquitination. These modifications play critical roles in altering protein structure, stability, activity, and localization, thereb......
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• Mass Spectrometry for Post-Translational Modifications
Mass spectrometry for post-translational modifications (PTMs) is an efficient tool that utilizes mass spectrometry technology to accurately identify and quantify protein mass spectrometry for post-translational modifications (PTMs). These modifications occur on specific amino acid residues after protein synthesis, either via enzymatic or non-enzymatic mechanisms, and include processes such as phosphorylation, acetylation, methylation, glycosylation, and ubiquitination. Mass spectrometry for post-trans......
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• Mass Spec Protein Quantification
Mass spec protein quantification is a technique based on mass spectrometry for quantitative analysis of proteins in biological samples. It finds extensive applications in proteomics, drug development, disease biomarker discovery, and molecular mechanism studies. Compared to traditional protein quantification methods like ELISA and Western Blot, mass spectrometry offers high throughput and broad coverage, allowing for simultaneous absolute or relative quantification of thousands of proteins. It also pr......
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Multiplex proteomics is a high-throughput proteomic strategy that utilizes mass spectrometry to identify and quantify thousands of proteins across multiple samples in a single experiment. This technique employs chemical or isotopic labeling methods, such as Tandem Mass Tag (TMT) and Isobaric Tags for Relative and Absolute Quantification (iTRAQ), to label proteins or peptides uniquely in each sample. These labeled samples are then mixed and analyzed in a single mass spectrometry workflow, allowing for ......
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• Mass Spectrometry Fingerprinting
Mass Spectrometry Fingerprinting is an advanced method leveraging mass spectrometry for both qualitative and quantitative analysis of biomolecules. By examining the mass-to-charge ratio (m/z) obtained from mass spectrometric data, this technique accurately identifies and quantifies diverse molecules within a sample. Widely utilized in biochemistry, pharmacology, and clinical diagnostics, mass spectrometry fingerprinting offers key advantages such as high sensitivity and specificity, enabling the analy......
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• Oligonucleotide LC-MS Analysis
Oligonucleotide LC-MS analysis is a powerful analytical technique used to separate and identify oligonucleotides. Oligonucleotides are short chains of nucleic acids consisting of a limited number of nucleotide units. The fundamental principle of liquid chromatography relies on the differential retention of oligonucleotides across stationary and mobile phases with varying chemical properties. By adjusting the composition and gradient of the mobile phase, effective separation of oligonucleotides can be ......
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Tandem MS/MS analysis is a highly sensitive and specific analytical technique that is extensively used in fields such as proteomics, metabolomics, environmental science, pharmaceutical analysis, and clinical diagnostics. This method extends the capabilities of traditional mass spectrometry (MS) by providing precise identification, quantification, and structural analysis of target molecules in complex samples. The process involves multiple stages of mass analysis, where molecular ions are fragmented, s......
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