Resources

• • Selection and Application of Molecular Weight Distribution Determination Methods

  Molecular weight distribution is an important parameter describing the range and relative content distribution of various biomolecule weights. In the field of biopharmaceuticals, understanding the molecular weight distribution of biomolecules is crucial for drug research and development and quality control. Scientists have developed various molecular weight distribution determination methods to meet the analysis needs of different types of biomolecules.   Gel Permeation Chromatography (GPC) Gel Permea......

• • Research Methods and Techniques for Proteomics

  Proteomics, as a discipline that studies the composition, structure, function, and interactions of all proteins in organisms, involves many research methods and technologies. These methods and technologies play a crucial role in proteomic research, helping us understand the characteristics and functions of proteins in depth.   Protein Separation and Purification Methods 1. Gel Electrophoresis Gel electrophoresis is a common protein separation method, including Polyacrylamide Gel Electrophoresis (PAGE)......

• • The Importance and Prospects of Acetylation Analysis in Disease Research

  Acetylation is an important post-translational modification method that plays a crucial role in regulating various biological processes within cells. With the advancement of proteomics technology, acetylomics as a cutting-edge science in the field of bioproduct research provides us with a new perspective to deeply understand the role of acetylation modification in different diseases.   Acetylation refers to a type of post-transcriptional modification formed by the combination of an acetyl group with t......

• • How to Choose the Appropriate Mass Spectrometry Analysis Technology for Proteome Determination

  Proteomics is the study of all the proteins in an organism, including their composition, structure, function, and interaction. It plays a pivotal role in revealing the physiological and pathological processes of the organism. In proteomics research, mass spectrometry is widely used for qualitative and quantitative analysis of proteins. However, with the continuous development of mass spectrometry technology, researchers face the challenge of choosing the appropriate mass spectrometry analysis techniqu......

• • Comparison and Selection of Shotgun Method and Other Protein Qualitative Methods

  A crucial task in proteomics research is to qualitatively analyze proteins to reveal their existence, nature, and functionality. Among the qualitative analysis methods, Shotgun Proteomics is a widely used technique. This article will detail the commonly used Shotgun Proteomics in proteomics and compare it with other qualitative methods, helping readers understand the principles and applications of Shotgun Proteomics and guiding the choice in protein qualitative research.

• • Peptide Sample Analysis in Peptide Identification Technology

  Identification and analysis of the biological world is a key step in deciphering any form of life science problem. Among these analyses, peptide identification technology, with its superior precision and profound complexity, occupies an important position in scientific research. Peptides are usually products of protein degradation, composed of different arrangements and conformations of several to several hundred amino acids, and can participate in or regulate many biological processes widely.

• • Methods Suitable for Accurate Analysis of Glycosylation Modifications

  Glycosylation is a common and important protein modification method that plays a key role in cell regulation. With the continuous development of the field of biopharmaceuticals, accurate detection of glycosylation modifications is increasingly important. Glycosylation modification detection can help us to deeply understand the structure and function of proteins, thereby optimizing the design and production process of biopharmaceuticals.   Mass Spectrometry: High-Resolution Identification of Glycosylat......

• • Deciphering the Complexity of the Proteome

  Proteins are essential functional molecules in biological bodies, playing key roles in regulation, catalysis, and structural support. Understanding the composition and expression changes of the proteome under different conditions is crucial for a deeper understanding of the functions of biological systems and disease mechanisms. Proteomics, as a discipline studying the proteome, utilizes sequencing technologies to decipher the complexity of the proteome, and has become a hot research direction in the ......

• • Comparison of Plasma Requirements for Different Samples in Proteomics

  Proteomics is an important biological research method that analyzes proteins in biological samples to reveal information about protein composition, function, and interactions within an organism. In proteomics research, plasma is one of the most commonly used sample types. This article will discuss the required plasma volume for different types of samples in proteomics research.

• • Metaproteome Analysis Technology Reveals the Complete Picture and Function of the Proteome

  Metaproteome analysis technology is a method for comprehensive study of the proteome in the body. In the past, scientists mainly relied on genomics studies to understand the genetic information of organisms. However, as the most basic functional molecules in the body, proteins play a key role in regulating life processes. Their types and functions are crucial to the normal operation of the body. Therefore, the emergence of metaproteome analysis technology fills this research gap.   Applications 1. Dev......