Resources

Proteomics Databases



Metabolomics Databases

• • 10x BCR Sequencing

  10x BCR sequencing is an advanced genomic technology specifically designed to investigate the complexity and dynamic changes of B cell receptors (BCRs). BCRs are essential components of the human immune system, responsible for recognizing and binding to foreign antigens, thereby initiating immune responses. By leveraging 10x BCR sequencing, researchers can gain in-depth insights into the processes of BCR gene recombination and somatic hypermutation, revealing how individual immune systems adapt to and......

• • De Novo Transcriptome Analysis

  De novo transcriptome analysis is a powerful approach for comprehensively profiling the transcriptome of organisms, particularly those lacking fully sequenced or annotated genomes. This technique enables researchers to capture the full spectrum of RNA molecules expressed under specific conditions, facilitating the elucidation of complex gene expression patterns and regulatory networks.   One of the key applications of de novo transcriptome analysis lies in gene discovery and functional annotation in n......

• • Single Cell Transcriptome Sequencing in Cancer and Neuroscience Research

  Single cell transcriptome sequencing is a powerful technique used to analyze gene expression profiles at the resolution of individual cells. It plays a vital role in modern biological research by revealing the molecular characteristics of cells under different physiological conditions. Its applications are particularly prominent in cancer research, where tumors are often composed of heterogeneous cell populations exhibiting distinct gene expression patterns and functional profiles. Single cell transcr......

• • 10x TCR Sequencing

  10x TCR sequencing is a cutting-edge technology designed to comprehensively profile the diversity and complexity of T cell receptors (TCRs). TCRs are protein complexes expressed on the surface of T cells, responsible for recognizing foreign antigens and initiating immune responses. Each T cell harbors a unique TCR sequence, and this diversity is a critical feature enabling the immune system to effectively detect and eliminate a wide array of pathogens. 10x TCR sequencing plays an essential role in bot......

• • Single Cell RNA Sequencing Technology

  Single cell RNA sequencing technology (scRNA-seq) has emerged as a pivotal tool in biomedical research, with wide-ranging applications in oncology, neuroscience, immunology, and developmental biology. In cancer research, scRNA-seq enables the identification of tumor heterogeneity, uncovering the molecular signatures of distinct cancer subtypes and informing the development of personalized treatment strategies. In neuroscience, the technology allows for the exploration of neuronal diversity and charact......

• • Single Cell Targeted Sequencing

  Single cell targeted sequencing (scTS) is designed to enable high-resolution analysis of specific genomic regions within individual cells. This approach offers distinct advantages for extracting detailed genetic information from complex biological samples. Traditional genomic sequencing methods typically require large numbers of cells, yielding population-averaged results that obscure cell-to-cell variability. In contrast, single cell targeted sequencing provides genome-level insights at single-cell r......

• • Single Cell RNA and DNA Sequencing

  Single cell RNA and DNA sequencing enables comprehensive profiling of the genome and transcriptome at the resolution of individual cells. Single cell DNA sequencing is primarily employed to uncover genomic alterations within individual cells, including copy number variations, point mutations, insertions and deletions, as well as complex structural rearrangements. This is particularly critical for understanding the pathogenesis of diseases such as cancer, where tumor cells often exhibit high degrees of......

• • Single Cell Next Generation Sequencing

  Single cell next generation sequencing (scNGS) is an advanced technique for characterizing genomic, transcriptomic, and epigenomic landscapes at the resolution of individual cells. In biomedical research, scNGS has been extensively employed to investigate cancer, immune-related disorders, and neurological diseases. Sequencing the genomes of individual tumor cells enables researchers to dissect intratumoral heterogeneity, thereby informing the development of personalized therapeutic strategies. Additio......

• • Single Cell Nucleic Acid Sequencing

  Single cell nucleic acid sequencing enables comprehensive genomic and transcriptomic analyses at the resolution of individual cells. This powerful technique allows scientists to uncover gene expression profiles across diverse cell types, providing insights into cellular function, state, and identity—even permitting the identification of rare cell populations. Its applications are broad, with one of the most impactful areas being cancer research. Tumors often exhibit significant cellular heterogeneity,......

• • X-Ray Crystallographic Analysis

  X-ray crystallographic analysis is a powerful technique used to elucidate the atomic and molecular structures of crystalline materials. In the realm of biology, the function of macromolecules such as proteins and nucleic acids is intricately linked to their three-dimensional conformation. By employing X-ray crystallographic analysis, researchers can obtain high-resolution structural information regarding conformational dynamics, active sites, and ligand-binding modes of these macromolecules, thereby e......