Resources
Proteomics Databases
Metabolomics Databases
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• Cyclic Peptide Sequencing Unveils Protein N-Terminal Structure and Function
Protein is an important functional molecule in organisms, and its structure and function are closely related. The N-terminal sequence of a protein plays a crucial role in determining its structure and function. However, due to the complexity and diversity of proteins, accurately determining the N-terminal sequence of a protein has always been a challenge.
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• The Methods for Detecting Amino Acid Sequences
The amino acid sequence is the fundamental building block of proteins in living organisms, and it is of great significance in studying protein structure, function, and interactions. Therefore, the development of efficient and accurate amino acid sequence detection methods is important for drug development in the field of biotechnology.
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• PRM Mass Spectrometry vs. ELISA: Decoding Protein Quantification
One of the important tasks in the field of biotechnology is protein quantification. Accurate measurement of protein abundance is crucial for understanding biological processes, disease diagnosis, and drug development. In protein quantification methods, Parallel Reaction Monitoring Mass Spectrometry (PRM) and ELISA are two commonly used techniques.
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• Shotgun Proteomics: Efficient Analysis of Complex Protein Samples
Proteins are important functional molecules in organisms and have significant implications for understanding physiological and pathological processes. However, traditional protein identification methods have limitations due to the complexity and diversity of proteins. In recent years, with the development of biotechnology, shotgun proteomics has become an important tool for researchers to decipher the protein composition in complex samples.
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• PRM Absolute Quantification: A Revolutionary Approach in Proteomics
Proteomics is an important approach to study the composition and function of proteins in organisms. In the past few decades, scientists have made significant breakthroughs in proteomics research through the continuous development of mass spectrometry techniques. Among them, quantitative mass spectrometry plays a crucial role in proteomics research.
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• PRM Proteomics: Applications in Disease Physiological Processes
With the continuous development of biotechnology, proteomics analysis has become an important approach to studying the composition and function of proteins in organisms. Among them, the quantitative mass spectrometry-based Parallel Reaction Monitoring (PRM) technique has gained considerable attention due to its high sensitivity, accuracy, and throughput. This article will explore the application prospects of PRM proteomics analysis in disease pathophysiology.
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• Recombinant Protein Drug Analysis Using Dynamic Light Scattering (DLS)
Recombinant protein drugs refer to protein products that originate from animals and plants and are developed through biotechnology research. These have certain biological activities that can prevent, treat, and diagnose diseases in humans and animals. Compared with small molecule drugs, recombinant protein drugs have advantages such as high activity, high specificity, and low toxicity, and are therefore favored by researchers.
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• Analysis of Thermal Stability of Recombinant Protein Drugs
Recombinant protein drugs refer to protein products that originate from animals or plants and are developed through biotechnology research. These products possess certain biological activities and are capable of preventing, treating, and diagnosing diseases in humans, animals, and plants. Compared to small molecule drugs, recombinant protein drugs have the advantages of high activity, high specificity, and low toxicity, and are thus highly favored by researchers.
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• Peptide Drug Residue Solvent Analysis
Peptide drugs are bioactive molecules formed by the connection of multiple amino acids through peptide bonds. Typically, they are composed of 10-100 amino acids, with a relative molecular weight less than 10,000. Most peptide drugs are derived from endogenous peptides or natural peptides, so they have little or no side effects on the human body. Compared with protein drugs, peptide drugs also have advantages such as good stability, high purity, low production cost, and low immunogenicity.
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• X-Ray Powder Diffraction Determination of Antibody Drug
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies. They achieve their therapeutic purpose by specifically binding with target molecules. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, antibody-drug conjugates, and others.
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