Resources
Proteomics Databases
Metabolomics Databases
-
• Nanopore Single Cell Sequencing
Nanopore Single Cell Sequencing is an advanced omics strategy that integrates single-cell isolation technologies with nanopore sequencing platforms, enabling high-resolution profiling of nucleic acid molecules within individual cells. At the single-cell level, sequencing technologies provide crucial insights into cellular heterogeneity, fate determination, and clonal evolution. Nanopore sequencing, characterized by its long-read capability, real-time signal acquisition, and direct RNA/DNA readout........
-
• B Cell Single Cell Sequencing
B cell single cell sequencing is an advanced analytical approach that integrates single-cell isolation techniques with high-throughput sequencing, specifically tailored to dissect the heterogeneity and functional states of B cells under various physiological and pathological conditions. As central players in the adaptive immune system, B cells are responsible for antibody production, antigen presentation, and the regulation of immune responses. Traditionally, immunological studies have treated B cells as...
-
• Cryo Electron Microscopy Protein Structure
Cryo electron microscopy protein structure refers to the study of protein three-dimensional conformations using Cryo-Electron Microscopy (Cryo-EM) under near-native conditions. With rapid advancements in imaging and computational techniques, this approach has emerged as a pivotal branch of structural biology, offering unmatched advantages in elucidating large macromolecular assemblies, membrane proteins, and highly flexible protein complexes. Traditionally dominated by X-ray crystallography and nuclear.....
-
• High-Throughput Cell-Based Assay
High-throughput cell-based assays refer to a modern biotechnology that enables rapid, quantitative, and systematic analysis of large numbers of cell samples through multiparametric and parallelized approaches on automated and miniaturized platforms. This methodology integrates advanced cell culture systems, multi-channel imaging technologies, fluorescence labeling techniques, and high-performance data analysis tools, allowing for the precise measurement of thousands of cell samples within a short time......
-
The CHO HCP assay is an analytical method for the quantitative detection of impurity proteins originating from CHO cells. CHO cells are widely used in the production of recombinant proteins, monoclonal antibodies, and cell therapies due to their high protein expression capacity, well-established culture systems, and efficient human-like post-translational modification capabilities. However, alongside the expression of target proteins, CHO cells also secrete a substantial number of...
-
The host cell DNA assay is a critical analytical technique used to quantify residual DNA in biopharmaceutical products. In biopharmaceutical manufacturing, recombinant proteins, monoclonal antibodies, and vaccines are typically expressed in host cells such as CHO cells, Escherichia coli, or yeast. However, during purification, residual host cell DNA may persist in the final product. Excessive residual DNA can pose safety concerns, including immunogenicity, carcinogenicity, and potential risks of genomic....
-
• Fundamental Methods and Techniques of Infrared Spectroscopy Analysis
Infrared (IR) spectroscopy is a technique used to identify chemical bonds and functional groups in both organic and inorganic samples. Its principle is based on the absorption of infrared light at specific wavenumbers (typically expressed in cm⁻¹) by chemical bonds within molecules, resulting in vibrational transitions. The following outlines the essential steps and key considerations in infrared spectroscopy analysis: Understanding the Basics IR spectra are generally divided into two regions: the......
-
• High-Content Screening Analysis
High-content screening analysis is a research platform focused on cell phenotyping that combines automated imaging, image recognition, and multi-parameter quantitative analysis. This technology is mainly employed to evaluate the functional effects of compounds, genes, or other interventions at the cellular level. One of its advantages is the generation of highly detailed data. Unlike traditional screening methods that offer only simple activity strength results, this technique provides high-dimensiona......
-
10x Genomics TCR sequencing is a powerful method for exploring the diversity and detailed characteristics of T-cell receptors (TCRs), which are essential for T-cells to recognize and bind to antigens in the immune response. This technology allows researchers to obtain comprehensive TCR sequence information, including diversity, clonal expansion, and unique sequence traits. In basic immunology, it provides an invaluable tool for systematically studying T-cell development, differentiation, and response ......
-
HTS drug screening is a technology-driven method that leverages automation, miniaturization, and parallel processing to assess the biological activity or mechanism of numerous candidate compounds efficiently. This approach significantly enhances the early stages of drug discovery, which are traditionally constrained by lengthy and costly processes. By simultaneously evaluating thousands to millions of samples, HTS drug screening has become a cornerstone of modern drug development. This technique is ......
How to order?
