Resources

Proteomics Databases



Metabolomics Databases

• • Advancing Antibody Research: The Power of Polyclonal Antibody Sequencing

  Discover how polyclonal antibody sequencing advances antibody research through reagent documentation, batch comparability, reproducibility, and sequence-informed experimental design.

• • What is the difference between native and denatured mass spectrometry?

  A practical comparison of native and denatured mass spectrometry covering key differences, decision dimensions, method selection by project goal, and complementary use in protein characterization.

• • What is Native Mass Spectrometry?

  A clear technical guide to native mass spectrometry covering definition, working principles, advantages, limitations, and common applications in protein and biotherapeutic analysis.

• • Native Mass Spectrometry (MS) Overview

  An overview of native mass spectrometry explaining what native MS measures, how it differs from other MS workflows, typical outputs, and key application areas in protein characterization.

• • PhIP-Seq Study Design for Disease and Control Cohorts

  A practical guide to PhIP-Seq study design for disease and control cohorts, covering inclusion criteria, control matching, sample size, matrix and library choice, batch planning, and analysis alignment.

• • Why PhIP-Seq Candidates Require Orthogonal Validation

  A technical guide explaining why PhIP-Seq candidates require orthogonal validation, covering false-confidence sources, validation pathways, and phased confirmation before autoantigen claims.

• • How to Interpret Enriched Peptides in Autoantibody Studies

  A practical guide to interpreting enriched peptides in autoantibody studies, covering normalization, control contrast, protein mapping, PTM context, and confidence tier assignment.

• • How PhIP-Seq Supports Candidate Autoantigen Discovery

  A technical guide explaining how PhIP-Seq supports candidate autoantigen discovery through library screening, enrichment analysis, protein mapping, and structured validation handoff.

• • PhIP-Seq for Autoantibody Profiling

  A technical overview of PhIP-Seq for autoantibody profiling covering workflow steps, library design, data outputs, applications, and validation planning.

• • Serum vs Plasma vs CSF for Autoantibody Profiling

  A comparison guide to serum, plasma, and CSF for autoantibody profiling covering matrix differences, study goal selection, handling requirements, and workflow implications.