Resources
Proteomics Databases
Metabolomics Databases
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• Exploring Strategies for Quantitative Analysis of Disulfide Bonds in Proteins
Disulfide bonds are important chemical bonds in proteins and are crucial for protein structure and function. Quantitative analysis of disulfide bonds is a key step in understanding protein structure and function. However, due to the unique properties of disulfide bonds, their quantitative analysis has always been a challenge in the field of biopharmaceuticals.
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• Analyzing Protein Structure Using Circular Dichroism Spectroscopy
The basic principle of circular dichroism spectroscopy is a technique used to study the structure of molecules by measuring their absorption and rotation of circularly polarized light. Chiral amino acid residues in proteins produce optical rotation effects on circularly polarized light and exhibit specific absorption spectra. Circular dichroism spectroscopy obtains structural information of proteins by measuring the difference in absorption of left- and right-handed circularly polarized light.
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• Selection and Optimization of Protein Identification Methods
Protein identification is the process of identifying and analyzing proteins, including determining their sequence, structure, modifications, and functions. This article will introduce the significance and challenges of protein identification, and focus on the selection and optimization of protein identification methods.
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• In-Depth Exploration of Methods and Applications for Detecting Protein Phosphorylation Levels
In organisms, protein phosphorylation is a common and important epigenetic modification that can regulate the structure and function of proteins. Phosphorylation modification can affect protein activity, interactions, and localization, thereby regulating biological processes such as cell signaling, gene expression, and cellular functions.
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• Unlocking the Epigenetic Field in Proteomics Research Through Methylation Detection
With the development of proteomics research, methylation detection has become a key technology in the field of epigenetics. Methylation, as one of the most common types of epigenetic modifications, plays a crucial role in gene expression and protein function.
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• Data Analysis and Mining Strategies in Proteomics Mass Spectrometry
Proteomic mass spectrometry technology is a key tool in the study of biological drugs, providing important information on the quality, sequence, and structure of protein samples for disease diagnosis and treatment. However, the massive amount of mass spectrometry data poses a challenge for researchers, as extracting meaningful information from these data and understanding their biological significance is a complex task.
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• Proteomics Analysis Technology Advancing Biological Research
Proteomics analysis techniques, which aim to comprehensively understand the protein composition and functions within an organism, have filled the research gap left by traditional methods due to the complexity and diversity of proteins. These techniques have revolutionized biological research.
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• Key Technologies in Protein Identification and Sequence Analysis
Protein identification and sequence analysis are crucial for understanding cellular processes, disease mechanisms, and biopharmaceutical development.
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With the advancement of technology, the De Novo sequencing of antibody protein allows us to accurately obtain the protein sequence information of antibodies, enabling in-depth study of their functions and their relationship with diseases.
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MtoZ Biolabs utilize GST Pull-Down kits, paired with a high-sensitivity UPLC-MS platform, to offer the most optimized one-stop solution for pull-down based protein analysis service. MS not only offers high sensitivity and specificity but also allows for the accurate identification of low-abundance and complex protein interaction networks. By applying MS to identify the proteins captured in the pull-down assay, it provides precise molecular-level information in a high-throughput context.
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