Resources
Proteomics Databases
Metabolomics Databases
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• Applications and Significance of Tandem Mass Spectrometry in Proteomics
Tandem mass spectrometry in proteomics has rapidly advanced in recent years and has become an important analytical technique.Proteomics is one of the key areas in biological research that focuses on the study of proteins, which play crucial roles in biological systems. It is of great significance for understanding cellular functions and disease mechanisms.
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• Development of Protein Modification Quantification Methods Based on Proteomics Analysis
Protein modification refers to the process of altering the biochemical characteristics and functions of proteins through covalent binding or non-covalent interactions.
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• Protein Analysis Revealing Protein Functions and Interactions
The techniques and methods for protein analysis include mass spectrometry analysis, electrophoresis analysis, spectroscopy analysis, and more. Mass spectrometry analysis provides information on protein composition, modifications, and quantification, which helps reveal the basis of protein function and interactions. Electrophoresis analysis can be used to separate and detect proteins, providing information on their size, charge, and purity.
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• Effects of DMSO on Protein Structure
Dimethyl sulfoxide (DMSO), as one of the commonly used solvents, has a certain impact on protein structure.In circular dichroism spectroscopy, the choice of solvent is crucial in maintaining the integrity of protein structure.
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• Analyzing Protein Secondary Structure Using Circular Dichroism Spectroscopy
Circular dichroism (CD) spectroscopy analysis has become an important tool in the field of biopharmaceutical analysis for studying protein secondary structure and providing critical information.
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• Diversity of Protein Glycosylation and Its Role in Biology
Protein glycosylation is a common and complex post-translational modification that adds sugar molecules to protein molecules. It regulates their structure, stability, and interactions, playing a crucial role in cellular function and biological processes. Protein glycosylation can be divided into two main types: N-glycosylation and O-glycosylation.
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• Protein Characterization Revealing Protein Structure and Functions
Protein characterization is an important means to reveal the structure, interaction, and function of proteins. Through common protein structure identification techniques, we can deeply understand the working principle of proteins and apply this knowledge in fields such as biology, drug development, and bioengineering.
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• How to Choose the Appropriate Polysaccharide Mass Spectrometry Identification Technique?
Accurate polysaccharide mass spectrometry identification and structural analysis of polysaccharides are crucial steps in understanding their characteristics and functions.
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• Assessing Drug Immunogenicity Through ADA Testing
As the use of antibody drugs increases, studies have found that some patients develop anti-drug antibodies (ADAs) after receiving treatment, which may have adverse effects on treatment efficacy and safety. Therefore, accurate assessment of drug immunogenicity has become a crucial task.
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• Exploring Methods and Techniques for Protein Crosslinking Experiments
Protein crosslinking experiments are important methods for studying protein-protein interactions. By chemically or physically linking specific sites within proteins, these experiments reveal the interaction networks and complex structures of proteins.
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