Resources
Proteomics Databases
Metabolomics Databases
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In recent years, RNA single cell sequencing has emerged as a revolutionary technology in the fields of biology and medical research. By enabling high-precision measurement of the transcriptomes of individual cells, this technique uncovers critical biological insights into cell heterogeneity within population samples. Unlike traditional RNA sequencing, which averages the expression levels across thousands of mixed cells, RNA single cell sequencing analyzes each cell individually, thus capturing unique ......
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• Advances in Single-Cell Sequencing
Single-cell sequencing is a powerful tool for analyzing genomic, transcriptomic, epigenomic, or proteomic information on an individual cell basis, thereby offering significant insights into cellular heterogeneity and function. Unlike traditional bulk sequencing, which aggregates signals from mixed cell populations, single-cell sequencing precisely captures the molecular characteristics of individual cells. This capability is crucial for elucidating the cellular composition of complex biological system......
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Discovery proteomics represents a key domain within proteomics, dedicated to identifying and characterizing previously unknown or biologically significant proteins through advanced high-throughput technologies. In contrast to targeted proteomics, discovery proteomics is not restricted to specific known proteins or biological pathways but aims to comprehensively profile all proteins and their potential functions within a given organism or physiological context. Its primary objective is to uncover the t......
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ICP Elemental Analysis is a highly precise analytical technique used for both qualitative and quantitative analysis of metallic and other elemental contents. The method involves introducing a sample into a high-temperature plasma, where elements are excited to emit light at characteristic wavelengths. The intensity of this light is measured by a spectrometer, allowing for the determination of the elemental composition within the sample. Owing to its high sensitivity, accuracy, broad detection range, a......
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Protein enrichment analysis is a bioinformatics approach designed to identify protein groups associated with specific biological processes, diseases, or experimental conditions from extensive proteomic datasets. By systematically screening and analyzing large-scale protein data, enrichment analysis highlights protein sets that demonstrate significant changes under defined conditions. This approach provides critical insights into protein functionality and dysregulation mechanisms, playing a pivotal rol......
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Comparative proteomics is a research methodology designed to identify differences and underlying mechanisms in protein composition, expression levels, modification states, and functional characteristics across diverse biological samples under distinct physiological or pathological conditions. The primary goal is to systematically compare proteins among multiple samples or experimental groups, generating critical data to elucidate biological processes. Unlike genomics or transcriptomics, proteomics pro......
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• Single Cell Protein Analysis
Single cell protein analysis is a transformative technology that enables the detection and quantification of intracellular protein composition and dynamic changes at single-cell resolution. Compared to traditional bulk proteomics methods, this approach offers significantly enhanced sensitivity and resolution, allowing researchers to study cellular heterogeneity and functional characteristics in unprecedented detail. In multicellular organisms, individual cells exhibit substantial diversity influenced ......
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• Protein Characterization Assays
Protein characterization assays are critical analytical techniques used to investigate the structure, function, and interactions of proteins. Proteins, as central molecules in cellular processes, perform diverse biological functions, including catalyzing biochemical reactions, transmitting cellular signals, and maintaining structural integrity. Through detailed analysis of the physical and chemical properties of proteins, these assays can provide insights into three-dimensional structures, post-transl......
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mAb characterization involves the comprehensive analysis and evaluation of the structure, function, and purity of monoclonal antibodies. In biotechnology and pharmaceutical development, mAbs are highly valued for their exceptional specificity and broad applications in disease diagnosis and therapy. Characterization aims to ensure the stability, efficacy, and safety of these biomolecules across development, production, and clinical use. Key aspects of mAb characterization include amino acid sequence ve......
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Protein pathway analysis is a fundamental technique in bioinformatics and systems biology, aimed at elucidating complex biological processes and functional mechanisms by studying proteins and their interaction networks. At its core, the analysis focuses on identifying and interpreting protein-protein interactions, offering insights into cellular functions, signaling pathways, metabolic networks, and disease mechanisms. By constructing protein interaction maps, researchers can identify functional modul......
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