Resources

Proteomics Databases



Metabolomics Databases

• • Mass Spectrometry Sequencing Method Analyzes Protein Structure and Function

  Proteins are one of the most important functional molecules in biological organisms, with their structure and function being closely related. Understanding the structure and function of proteins is of significant importance for a deeper understanding of the life activities of organisms. Mass spectrometry sequencing, as a highly efficient and accurate protein analysis technology, provides us with a powerful tool for revealing the structure and function of proteins.

• • How Is the Amino Acid Sequence of a Peptide Determined?

  Peptides are large biological molecules composed of amino acids. The determination of their amino acid sequence is of great significance for drug development in the field of biotechnology. This article will introduce the methods of determining the amino acid sequence of peptides and its application in drug development.   Edman Degradation Method The Edman degradation method is one of the earliest methods used to determine the amino acid sequence of peptides.

• • Advancing Protein Gel Bar Identification: Breakthrough in HPLC Protein Purity Detection

  Proteins are important functional molecules in biological systems and play a crucial role in understanding biological processes and the development of biological drugs. During the development of biological drugs, accurate identification of protein purity is crucial.

• • How to Read Protein Amino Acid Sequence?

  Basic Composition of Amino Acid Sequence The amino acid sequence of a protein is composed of 20 different amino acids in a certain order. Each amino acid has its own characteristics and chemical properties, which determine the structure and function of proteins. When interpreting the amino acid sequence, we need to pay attention to the following aspects:

• • What is the Analysis Flow for Protein Amino Acid Sequence Testing?

  Proteins are important functional molecules in organisms, and their amino acid sequences determine their structure and function. Therefore, accurately determining the amino acid sequence of proteins is of great importance for drug development in the biotechnology field. This article will introduce the analysis process of protein amino acid sequence testing methods, including sample preparation, sequencing technology, data analysis, and result interpretation.

• • DLS (Dynamic Light Scattering) Analysis of Antibody Drugs

  Antibody drugs are a class of drugs that treat diseases through artificially synthesized antibodies, such as monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, antibody drug conjugates, etc. They bind specifically with target molecules to achieve therapeutic purposes. Antibody drugs have shown significant therapeutic effects in many disease treatments, such as cancer, autoimmune diseases, inflammatory diseases, immune regulation, and ophthalmic diseases.

• • Circular Dichroism Detection of Recombinant Protein Drugs

  Recombinant protein drugs are protein therapeutic drugs produced using DNA recombination technology or other biotechnologies. They include cytokines, polypeptide hormones, recombinant enzymes, monoclonal antibodies, fusion proteins, etc. Compared with traditional low-molecular synthetic drugs, recombinant protein drugs have the advantages of high specificity, low toxicity, and significant therapeutic effects.

• • Analysis of Peptide Drugs: HCP and HCD

  Peptide drugs are bioactive molecules made up of multiple amino acids linked by peptide bonds. Typically, it consists of 10 to 100 amino acids and has a relative molecular mass below 10,000. Most peptide drugs are derived from endogenous peptides or natural peptides, so they have little or no side effects on the human body. Compared to protein drugs, peptide drugs also have advantages such as good stability, high purity, low production cost, and low immunogenicity.

• • Protein Gel Mass Spec: Pros and Cons of Sample Submission

  Proteins are significant functional molecules in organisms, and the study of their structure and function is crucial for understanding life activities. Proteomic analysis is a common technique that can provide information about the structure and composition of proteins. In proteomic analysis, protein gel strip samples are one of the commonly used sample types. This article will focus on the submission methods for proteomic analysis of protein gel strip samples, exploring their pros and cons.

• • What is the Primary Structure of a Protein?

  The primary structure of a protein refers to the linear arrangement of amino acids in the protein. In other words, it is the structure formed by connecting the individual amino acids in a specific order in the protein. Proteins are composed of 20 different amino acids, each with its unique side chain. These amino acids are connected by peptide bonds to form a peptide chain.