Resources

Proteomics Databases



Metabolomics Databases

• • Top-Down and Bottom-Up Proteomics

  Top-Down and Bottom-Up Proteomics represent two primary strategies in proteomic research, each offering distinct advantages and applications. Top-Down Proteomics involves the analysis of intact proteins using mass spectrometry, preserving the protein's natural state. This approach is particularly valuable for investigating post-translational modifications and protein isoforms. Conversely, Bottom-Up Proteomics entails the enzymatic digestion of proteins into peptides, which are then analyzed by mass sp......

• • Interactome Map

  The interactome map represents a comprehensive and systematic depiction of the interactions among various biomolecules, including proteins, nucleic acids, lipids, and metabolites, within an organism. By graphically representing these complex networks, it serves as a "map" that enables researchers to intuitively understand how biological processes and cellular functions are regulated through these molecular interactions. In recent years, this technology has garnered significant attention and applicatio......

• • Protein Identification and Characterization

  Protein identification and characterization are critical components of proteomics research, aimed at thoroughly analyzing the types, structural features, and functional information of proteins within biological samples. As the final products of gene expression, proteins engage directly in and regulate nearly all biological processes, with a complexity in type and function that far surpasses nucleic acids. The primary tasks in protein identification and characterization involve two main aspects: identi......

• • How to Interpret Dynamic Light Scattering Analysis Results

  Dynamic Light Scattering (DLS), also known as laser scattering or quasi-elastic light scattering, is a technique used to measure the Brownian motion of small particles and molecules in a fluid. This technique provides information on particle size, shape, and distribution.

• • E. coli Gene Knockout Service

  Service Features: 1. High Efficiency: Leveraging advanced biotechnological methods, we can efficiently and accurately knock out specific genes in Escherichia coli. 2. Precision: Our service allows for the precise knockout of target genes based on client specifications, ensuring no disruption to other gene functions. 3. Safety: Our technicians undergo rigorous training to ensure the safe execution of all experimental procedures.

• • Detection of Protein Redox Modifications

  Protein redox modification represents a crucial post-translational modification in living organisms, involving structural changes in proteins and functional regulation. This process has profound implications for diverse physiological and pathological mechanisms, highlighting the importance of studying and detecting protein redox modifications.

• • Nitrosation Protein Modification Site Identification

  Nitrosylation is a crucial post-translational modification of proteins that plays a significant role in various physiological and pathological processes, including cell differentiation, apoptosis, tumor development, and neurodegenerative diseases. Identifying nitrosylation sites is essential for elucidating its biological functions.

• • Ubiquitination Site Detection by IP-MS

  IP-MS is a powerful technique for identifying ubiquitination sites on proteins, combining immunoprecipitation (IP) with mass spectrometry (MS) to achieve precise identification. This method is particularly noted for its capacity to conduct detailed analyses of ubiquitination at specific protein sites, providing insights into the ubiquitination of individual or multiple proteins. Furthermore, when integrated with mass spectrometry, IP-MS enables the analysis of protein diversity, post-translational..........

• • Co-IP Detects Protein Ubiquitination

  Protein ubiquitination is a critical post-translational modification with significant implications in various biological processes, including the regulation of the cell cycle, gene transcription, and DNA repair. Co-immunoprecipitation (COIP) is a widely employed technique to assess protein ubiquitination.

• • Mass Spectroscopy for Protein Analysis

  Mass spectroscopy for protein analysis is an advanced technique for examining the composition, structure, and function of proteins. By leveraging the high sensitivity and resolution of mass spectrometry, this method allows researchers to precisely identify and quantify complex protein mixtures. In modern life sciences, it is a cornerstone technology widely employed in biomedical research, drug development, and molecular biology. This powerful technique enables scientists to unravel protein functions, ......