Resources

• • Amino Acid Analysis Methods for Protein Diversity Studies

  Amino acids are the fundamental building blocks of proteins, and their composition and sequence determine the structure and function of proteins. Therefore, the analysis of amino acids is of great significance for understanding the diversity of proteins.

• • Sample Preparation in Amino Acid Analysis

  Amino acid analysis is an important technique in the field of biopharmaceuticals, and it has significant implications for drug development, production, and quality control. However, the accuracy and reliability of amino acid analysis largely depend on the quality of sample preparation.

• • PI Detector Unveiling the Mystery of Protein Conformation

  In the microscopic realm of the biological world, our eyes cannot directly see proteins. Proteins, like numerous "chemical workers," are involved in complex biochemical reactions within our bodies. However, did you know that these "chemical workers" are diverse and their behavior in our bodies is equivalent to charges in an electric field? Technically, this is referred to as the isoelectric point or pI value.

• • Amino Acid Composition Analysis for Protein Helical Structure Identification

  Amino acid composition analysis (also known as amino acid quantification analysis) is a technique that involves hydrolyzing, eluting, and detecting amino acids in a biological sample using methods such as high-performance liquid chromatography or capillary electrophoresis. The analysis provides information on the content and ratio of each amino acid, which can be used to understand the nature, function, and stability of protein samples.

• • Purity and Size Analysis of Inactivated Vaccine Virus Particles

  Inactivated vaccines refer to vaccines made by culturing and inactivating pathogenic microorganisms, and they are a common type of vaccines. For viral inactivated vaccines, viral structural proteins are one of the most important components, including surface proteins and capsid proteins. Viral structural proteins are critical factors in the virus life cycle and host infection, and they are also the main target for immune response triggered by vaccines.

• • Infrared Spectral Analysis of Vaccine Carrier Proteins

  Combined vaccine carrier protein refers to a protein product derived from animals or plants through biotechnological research and development, with certain biological activity. Compared to small molecule drugs, combined vaccines have advantages such as high activity, high specificity, and low toxicity, making them favored by researchers. The understanding of the structure of the combined vaccine carrier protein is crucial for understanding its function and stability.

• • Disulfide Bond Mapping in Recombinant Protein Drugs

  Recombinant protein drugs are a class of drugs with proteins as the main active ingredients. Their molecular weight is usually much larger than traditional small molecule drugs, and their structure is more complex. Recombinant protein drugs can directly act on molecular mechanisms in the body, possessing high specificity, strong biological activity, and relatively low side effects.

• • Mass Spectrometry Reveals Links Between Exosomal Proteins and Cell Development

  Proteomics is a research field that uses mass spectrometry to identify and quantify proteins on a large scale in biological tissues and cells. Through proteomic techniques, comprehensive information about tissues, cells, and even individual proteins can be obtained, broadening our understanding of biological processes.

• • Mass Spectrometry Revealing Molecular Mechanisms in Proteomics

  Mass spectrometry analysis is a powerful tool that can accurately and effectively analyze the mass, chemical structure, and relative abundance of substances. In the field of biological drug research, it has various applications in the study of proteins, such as quantification, identification, and protein-protein interactions.

• • Quantitative Analysis of Tyrosine Phosphorylation by LC-MS/MS

  Tyrosine phosphorylation is a critical regulatory mechanism in cellular signal transduction, deeply involved in controlling key biological processes such as cell proliferation, differentiation, and apoptosis. As a reversible post-translational modification, it plays a central role in numerous diseases, including cancer, autoimmune disorders, and neurodegenerative diseases.