Resources

Proteomics Databases



Metabolomics Databases

• • Proteomics Target Identification

  Proteomics target identification is pivotal in contemporary research within biomedical and life sciences, serving as a methodology to pinpoint protein targets linked to specific biological processes, diseases, or pharmacological actions. As primary agents of cellular functions, proteins play an indispensable role in organismal biology. Comprehensive insights into proteins involved in particular biological processes and their interactions are crucial for elucidating the molecular mechanisms underpinnin......

• • Protein Sequence Determination

  Protein sequence determination is the process of identifying the sequence of amino acids in a protein molecule. This is crucial in fields such as molecular biology, structural biology, and biochemistry, as the function of a protein is inherently linked to its amino acid sequence. By determining this sequence, scientists can infer a protein's three-dimensional structure, its functional properties, and how it interacts within the cell. Furthermore, protein sequence determination is essential in medicine......

• • Proteomic Analysis of Exosomes

  Proteomic analysis of exosomes is an integral technique in contemporary biomedical research, aimed at comprehensively characterizing the types and functions of proteins within exosomes. Exosomes are small vesicles, 30-150 nanometers in diameter, secreted by cells. They facilitate the intercellular and fluid-based transfer of biomolecules, including proteins, lipids, and nucleic acids. Playing pivotal roles in cell communication, waste removal, and immune response regulation, exosomes are crucial for u......

• • Proteomics LC-MS/MS

  Proteomics LC-MS/MS analysis is a powerful tool for comprehensive protein profiling and identification in biological samples. LC-MS/MS, which stands for liquid chromatography-tandem mass spectrometry, enables the separation, detection, and characterization of complex protein mixtures. This technique provides critical insights into protein identification, quantification, and post-translational modifications, playing a pivotal role in elucidating protein function, cellular signaling pathways, and diseas......

• • Protein Thermal Stability Assay

  The protein thermal stability assay is a critical method for examining the structural and functional resilience of proteins under conditions of thermal denaturation. This technique involves applying heat to assess structural changes in proteins, thereby evaluating how different temperatures influence their stability. Protein thermal stability is defined as the capacity of a protein to preserve its native conformation and function at elevated temperatures. This assay is extensively employed in drug dev......

• • Proteomics Bottom-up & Top-down

  Proteomics bottom-up & top-down approaches are two fundamental strategies in modern life sciences, primarily used to investigate the composition and functional properties of proteins in biological samples. Bottom-up proteomics involves enzymatic digestion of proteins into peptides, followed by mass spectrometry (MS) analysis to reconstruct protein-level information. In contrast, top-down proteomics directly analyzes intact proteins via MS without enzymatic digestion, thereby preserving post-translatio......

• • Proteome Analysis by Mass Spectrometry

  Proteome analysis by mass spectrometry is a powerful technique for investigating the composition, structure, function, and interactions of proteins in biological samples. As essential biomolecules, proteins participate in nearly all biological processes, including cellular architecture, signal transduction, metabolic regulation, and immune responses. By fractionating complex protein mixtures and performing qualitative and quantitative analyses, this approach enables a comprehensive understanding of ce......

• • Protein Stability Analysis

  Protein stability analysis is a scientific approach used to evaluate a protein’s ability to retain its structural integrity and functionality under varying environmental conditions. As essential biomolecules, proteins not only provide structural support to cells and tissues but also function as enzymes, signaling molecules, and transport carriers in biochemical processes. Protein stability analysis has broad applications across drug development, industrial enzyme engineering, food science, and fundame......

• • MS/MS Proteomics

  MS/MS Proteomics, or tandem mass spectrometry proteomics, is an advanced analytical technique used to explore the protein composition and structure of biological samples in depth. By fragmenting proteins into peptide sequences, mass spectrometry enables the identification and quantification of proteins. This method is indispensable in biological and medical research because proteins are integral to cellular functions. Understanding how protein expression changes under various biological states and con......

• • Flow Cytometry Protein Quantification

  Flow cytometry protein quantification is a high-throughput analytical technique grounded in flow cytometry, enabling precise measurement of target protein expression at the single-cell level. This method uses fluorescently labeled antibodies that bind specifically to target proteins, with a flow cytometer detecting the intensity of the fluorescence signals to quantify protein expression within a cell population. Unlike traditional protein quantification methods such as Western blot or ELISA, flow cyto......