Resources
Proteomics Databases
Metabolomics Databases
-
Olink analysis is a high-throughput immunoassay platform technology designed for rapid and precise protein quantification. Leveraging Olink's unique Proximity Extension Assay (PEA) technology, researchers can simultaneously detect hundreds to thousands of protein biomarkers, significantly accelerating biomarker discovery and validation. PEA employs two antibodies that bind to the target protein, one carrying an extension probe. Upon binding, the probes form a complete DNA sequence, which is then detec......
-
• Glycan Analysis of Monoclonal Antibody
The glycan analysis of monoclonal antibody is a crucial research area in biopharmaceuticals and biotechnology. Monoclonal antibodies are highly specific therapeutic proteins widely used to treat diseases such as cancer, immune disorders, and infectious diseases. This analysis focuses on detailed characterization of glycosylation patterns, a type of post-translational modification present in both the constant and variable regions of antibodies. Glycosylation profoundly influences antibody structure, st......
-
Label-Free Quantification is a widely used technique in proteomics that directly measures the relative abundance of proteins in a sample using mass spectrometry, eliminating the need for chemical or isotope labels. This approach relies on detecting and comparing signal intensities across different conditions to infer protein abundance. Its simplicity and versatility have made it an essential tool across biomedical research, drug development, disease mechanism studies, and agricultural science. In bi......
-
To identify protein is to accurately detect and characterize specific proteins within biological samples using advanced technical methodologies. The ability to identify protein is fundamental to understanding their biological functions, as protein activity and function are intrinsically tied to their structure and molecular interactions. This process is not merely about confirming the presence of proteins but also serves as the basis for comprehending their biological roles within cellular contexts. A......
-
• Edman Degradation Sequencing
Edman degradation sequencing is a classic method used to determine the primary structure of proteins. This technique chemically modifies the N-terminal amino acid of a protein, enabling its stepwise removal from the N-terminus. This process generates a series of identifiable derivatives, facilitating the analysis of protein sequences. Specifically, the method involves the reaction of an isothiocyanate acyl derivative with the N-terminal amino acid of the polypeptide chain, producing a phenylthiohydant......
-
Protein Quality Assessment is a critical technique in modern biological and medical research, designed to evaluate the purity, integrity, functionality, and biocompatibility of protein samples. This process is essential for ensuring that protein components in biologics, drug development, and the food industry meet the required standards. Protein quality assessment is not limited to biopharmaceutical applications but is also widely used in food safety testing, nutritional research, environmental monito......
-
Top-down mass spectrometry is a technique used in proteomics to analyze intact proteins directly, without the need to cleave them into peptides, as in the traditional "bottom-up" approach. This method significantly enhances the resolution and accuracy of proteomic studies, especially in the investigation of post-translational modifications, polymorphisms, and isoforms of proteins. Top-down mass spectrometry provides detailed structural information about proteins, including the precise locations and ty......
-
• Gas Chromatography Mass Spectrometry Analysis
Gas Chromatography Mass Spectrometry analysis is a powerful analytical technique that combines gas chromatography and mass spectrometry, widely used in the fields of chemistry and biology for the separation and identification of complex mixtures. During the gas chromatography phase, compounds in the sample are separated based on their differing distribution coefficients between the gas mobile phase and the stationary phase. These separated compounds then enter the mass spectrometer, where they are io......
-
LC-MS/MS analysis combines the strengths of liquid chromatography (LC) and mass spectrometry (MS), enabling the efficient separation and precise analysis of complex samples. In this analysis, LC is used to separate the various components of a sample, while tandem mass spectrometry (MS/MS) detects and identifies these separated components. In LC, compounds are separated based on their chemical properties, such as polarity, size, or molecular structure, through interactions between the mobile and stati......
-
Epitope Mapping is a technique used to characterize the interactions between antibodies and antigens and to identify antigenic epitopes. An antigen epitope is a specific region of a protein that can be recognized and bound by the immune system, typically by antibodies or T cell receptors. Epitope mapping is widely applied in biomedical research for vaccine design, diagnostic tool development, and studying the mechanisms of autoimmune diseases. By identifying antigenic epitopes, researchers can gain a......
How to order?
