Resources

Proteomics Databases



Metabolomics Databases

• • Single-Cell Sequencing Immune Cells

  Single-cell sequencing immune cells has emerged as an innovative technology in recent years, designed to analyze the genomic, transcriptomic, or other omics data of individual immune cells. Traditional sequencing methods typically rely on mixed samples from large populations of cells, which can obscure cell heterogeneity, resulting in the loss of critical information. In contrast, single-cell sequencing immune cells overcomes this limitation. By sequencing individual cells, researchers can uncover the......

• • Single-Cell Sequencing Technology

  Single-cell sequencing technology is an advanced genomic analysis approach designed for investigating the genome, transcriptome, and epigenome of individual cells. Traditional sequencing methods typically require large numbers of cells, and the resulting data represents averages across cell populations, thus failing to capture the specific differences of individual cells. However, organisms are composed of diverse cell types, each with its unique functions and gene expression profiles. Single-cell seq......

• • Single-Cell Sequencing from Frozen Tissue

  Single-cell sequencing from frozen tissue is a biotechnology designed to deconstruct complex tissue samples to the single cell level and carry out comprehensive analyses, such as genomic and transcriptomic analyses. This technology is particularly well-suited for preserved tissue samples, allowing researchers to collect high-quality single cell data while maintaining sample integrity. The introduction of this technology has significantly advanced medical research, particularly in the areas of tumor he......

• • Host Cell Protein Assay

  Host cell protein assays are crucial techniques used to assess the residual amounts of exogenous proteins derived from production cells in biopharmaceutical products. These proteins may be inadvertently introduced during the manufacturing of biologics and can persist in the final product despite purification efforts. The presence of HCPs can compromise drug safety and efficacy, potentially triggering immune responses or interfering with the intended therapeutic functions. As such, host cell protein as......

• • Advancements in Targeted Drug Delivery Systems

  Targeted drug delivery systems represent a crucial area in contemporary medical research, aimed at enhancing the precision and effectiveness of therapeutic interventions. Traditional drug delivery methods encounter challenges such as uneven drug distribution, limited drug half-life, and substantial side effects, which can restrict therapeutic efficacy and patient tolerance. Targeted drug delivery systems utilize specific carriers to precisely deliver drugs to affected sites, thereby increasing drug co......

• • Tandem Mass Spectrometry Protein Sequencing

  Tandem mass spectrometry protein sequencing is a pivotal technique for determining the sequence and structural characteristics of protein molecules. By integrating liquid chromatography with mass spectrometry, it enables the identification and quantification of proteins within complex biological samples. The fundamental principle involves initially fragmenting protein samples into smaller peptides using a mass spectrometer, followed by further fragmentation of these peptides to glean detailed structur......

• • Charge Variant Analysis

  Charge variant analysis is an important method in proteomics, primarily used to investigate the subtle structural variations of proteins and their impacts on biological function. As key molecules in life processes, the structure and charge state of proteins influence their physiological functions in organisms. During protein synthesis and post-translational modifications, various charge variants may arise. While these variants are nearly identical in amino acid sequence, they may differ in isoelectric......

• • Host Cell Protein Analysis in Biopharmaceuticals

  Host cell protein analysis is an essential technique in the biopharmaceutical industry, primarily aimed at detecting and analyzing residual host cell proteins in biopharmaceutical products. These proteins, expressed by host cells such as E. coli, yeast, or mammalian cells during biopharmaceutical production, are non-product-related. When recombinant DNA technology is used to produce a drug, residual host cell proteins are inevitably present, often in trace amounts. The primary objective of host cell p......

• • Protein Purification and Characterization

  Protein purification and characterization is a fundamental aspect of modern life sciences research. It involves a range of advanced techniques to isolate target proteins from complex biological samples and conduct comprehensive analyses of their physicochemical properties, structural characteristics, and functions. As essential molecules in life processes, proteins participate in nearly every biological function. Through systematic purification and characterization, researchers can accurately delineat......

• • Protein Qualitative Analysis

  Protein qualitative analysis is a crucial technique in proteomics research, aimed at identifying the protein composition of complex biological samples and analyzing their structural and functional properties. As key molecules in biological processes, proteins carry out a wide range of functions in organisms, such as catalyzing chemical reactions, transmitting signals, and maintaining cell structure. Utilizing advanced analytical techniques, protein qualitative analysis helps researchers identify the s......