Resources

Proteomics Databases



Metabolomics Databases

• • Label-Free Quantitative Analysis of Plant Proteins

  Proteins are among the most crucial molecules in living organisms, participating in nearly all biological processes. Plant proteins play essential roles in growth, development, environmental adaptation, and disease resistance. To fully understand the dynamic changes and functions of plant proteins, proteomics has become an indispensable tool in biological research.

• • iTRAQ-Based Quantification of Plant Proteomic Changes

  Plant proteomics is the scientific study of the composition, structure, and function of proteins within plants, providing insights into molecular mechanisms under various growth stages, environmental conditions, and stress responses. In recent years, quantitative proteomic analysis has become a crucial tool for studying physiological and metabolic changes in plants, facilitated by the advancement of mass spectrometry (MS) technology.

• • Quantitative Analysis of Serum Proteins Based on LC-MS/MS

  As modern biology and medical research advance, the quantitative analysis of serum proteins has become an essential tool for evaluating physiological and pathological states. LC-MS/MS (liquid chromatography-tandem mass spectrometry) is a highly sensitive, selective, and accurate quantitative method widely used in serum protein analysis. It enables the identification and quantification of low-abundance proteins in serum, providing strong support for biomarker discovery and disease mechanism research.

• • Subcellular Membrane Proteomics Analysis via Nano-LC-MS

  Subcellular membrane proteomics analysis plays a critical role in uncovering the dynamic changes and functional characteristics of proteins located in different membrane regions, organelles, and subcellular structures. These proteins are essential for cellular signaling, material transport, and cell-cell interactions.

• • Workflow of Immunopeptidomics

  Immunopeptidomics is a specialized field within immunology focused on studying peptide molecules involved in antigen presentation by analyzing peptides bound to major histocompatibility complex (MHC) molecules. The field seeks to identify pathogen, tumor, or aberrantly expressed peptides presented on the surface of cells, aiding in the design of vaccines, cancer immunotherapies, and the study of autoimmune diseases.

• • Principle of Immunopeptidomics

  Immunopeptidomics is a field of study that employs mass spectrometry (MS) to investigate peptides related to the immune system. The focus is on detecting and analyzing antigenic peptides presented by the major histocompatibility complex (MHC). These antigenic peptides, typically 8-15 amino acids long, are fragments of intracellular proteins that are processed and presented on the cell surface by MHC molecules. They are then recognized by T-cell receptors (TCRs), triggering an immune response.

• • Application of Mass Spectrometry in Peptidomics

  Peptidomics is a branch of proteomics that focuses on studying peptides' composition, structure, function, and dynamic changes in biological samples. It plays a significant role in protein identification, biomarker discovery, and drug development. Mass spectrometry (MS), a highly sensitive and accurate analytical technique, has become widely used in peptidomics.

• • Workflow of Peptidomics for Endogenous Peptide Analysis

  Peptidomics is a critical sub-discipline that investigates the composition, structure, function, and dynamics of peptides in biological samples. Endogenous peptides, short-chain molecules generated by the degradation of proteins or non-translational pathways, play pivotal roles in various physiological processes, including signal transduction, immune regulation, and metabolic control.

• • Advantages and Limitations of Peptidomics in Biological Sample Analysis

  Peptidomics, a large-scale analysis technique focused on peptide molecules, has gained widespread application in biomedical research in recent years. As a vital branch of proteomics, peptidomics provides in-depth insights into specific physiological or pathological states by directly studying peptide molecules in biological samples. Scientists mainly analyze naturally occurring small peptides within biological specimens, such as blood, urine, and cerebrospinal fluid.

• • Aseptic Testing of Recombinant Protein Vaccines

  Recombinant protein vaccines are a type of vaccine that does not contain complete pathogens, but is formulated with specific protein antigens produced in heterologous expression systems. Recombinant protein vaccines have become increasingly popular among researchers in recent years due to their advantages such as good safety, strong stability, and low cost.