Resources

Proteomics Databases



Metabolomics Databases

• • Gene Knockout and Western Blot Validation Service

  Gene knockout represents a critical technique in biological research for elucidating gene functions. By eliminating specific genes, researchers can observe phenotypic changes in organisms, thus uncovering gene roles. Nevertheless, gene knockout remains a sophisticated and labor-intensive procedure necessitating advanced tools and methodologies. We provide specialized gene knockout services designed to facilitate the execution of these experiments with precision and efficiency.

• • Detection of the Immunogenicity of Type III Collagen

  Collagen is a crucial structural component of tissues, predominantly found in the skin, bones, tendons, blood vessels, and other connective tissues. Type III collagen belongs to the collagen family, and assessing its immunogenicity is essential for understanding its role in disease onset and progression.

• • 4D-PRM Quantitative Proteomics

  As biological research progresses, proteomics, which seeks to elucidate the function, structure, and regulation of all proteins, has become a crucial part of biological studies. Recently, the emerging technology known as 4D-PRM (Four-Dimensional Parallel Reaction Monitoring) has garnered significant attention from researchers. This technique addresses the limitations of traditional quantitative proteomics by delivering precise protein quantification data.

• • Knockout Cell Line Service

  Gene knockout represents a crucial methodology in molecular biology for elucidating gene functions within organisms. Our gene knockout cell line service is specifically designed to facilitate researchers in the efficient and swift acquisition of targeted gene knockout cell lines.

• • Peptide Quantification Mass Spectrometry

  Peptide quantification mass spectrometry is a precise mass spectrometry-based analytical technique for quantifying specific peptides in protein samples. In proteomics, this method is essential for investigating protein expression dynamics in biological systems. By precisely measuring the relative or absolute abundance of peptides, researchers can gain deeper insights into biological processes, disease mechanisms, and drug responses. Peptide quantification mass spectrometry is widely applied in biomark......

• • Peptide Sequence Analysis

  Peptide sequence analysis refers to the process of determining and analyzing the sequences of peptides derived from protein digestion using techniques such as mass spectrometry (MS) and chromatography. This process is a core step in proteomics research, as the function and structure of proteins are determined by their amino acid sequences. Therefore, obtaining peptide sequence information is essential for understanding protein properties and functions. Peptide sequence analysis not only helps scientis......

• • Peptide Mass Mapping in Proteomics

  Peptide mass mapping is an analytical technique in proteomics. Its core principle relies on mass spectrometry to measure the mass of peptides, allowing researchers to infer their amino acid sequences and corresponding source proteins. By precisely determining peptide masses and integrating bioinformatics analysis, this approach enables both qualitative and quantitative analysis of complex protein mixtures. This is essential for understanding protein function, structure, and interactions within biologi......

• • Applications and Challenges of Native Mass Spectrometry in Proteomics

  Native mass spectrometry is an innovative approach for protein analysis that has garnered increasing attention in proteomics research. As life sciences research continues to advance, proteomics has become an indispensable tool for deciphering biological processes, disease mechanisms, and molecular functions. It plays a pivotal role in fundamental research, clinical diagnostics, and drug development. However, the inherent complexity and diversity of proteins present significant challenges to comprehens......

• • Key Techniques and Development History of Native Mass Spectrometry

  Native mass spectrometry is an advanced technique that enables the direct determination of protein mass, structure, and post-translational modifications without disrupting their native conformation. Unlike traditional enzymatic digestion-based mass spectrometry, native mass spectrometry preserves the high-order structure and multi-subunit composition of proteins during ionization, allowing researchers to analyze protein complexes, molecular interactions, and regulatory mechanisms of protein function w......

• • Native Mass Spectrometry: Principles, Advantages, and Applications

  Native mass spectrometry is an emerging technique in mass spectrometry that allows for the direct analysis of intact protein molecules, providing insights into their native structures and post-translational modifications. It has become increasingly significant in proteomics research. In the following sections, we discuss its fundamental principles, advantages for proteomics, and various applications.   Principles The core principle of mass spectrometry is to ionize the sample and measure its mass-to-c......