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10x Genomics DNA sequencing, as a leading high-throughput sequencing technology, enables comprehensive and detailed genomic analysis by integrating droplet microfluidics with advanced single-cell capture methods. This technique is widely applicable in various fields, including cancer genomics, genetic disease analysis, and evolutionary biology. In cancer research, 10x Genomics DNA sequencing facilitates single-cell analysis of tumor samples, allowing researchers to identify and monitor genetic heterog......
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10x genome sequencing is an advanced single-cell sequencing technology designed to reveal the genetic diversity and complexity of individual cells by analyzing their genomic information. This technology demonstrates broad application potential across various biomedical fields, including cancer research, developmental biology, immunology, and neuroscience. In cancer research, 10x genome sequencing enables scientists to identify clonal heterogeneity within tumors. By sequencing the genomes of individu......
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10x Chromium sequencing technology is a cutting-edge tool for analyzing the complexity of genomes, transcriptomes, and epigenomes at the single-cell level. By precisely barcoding RNA and DNA molecules within individual cells, this technology enables researchers to delve deeply into cellular heterogeneity and dynamic changes. The applications of 10x Chromium sequencing are extensive, spanning oncology, immunology, neuroscience, and developmental biology. In oncology, this technology offers new insights......
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10x V (D) J sequencing represents a cutting-edge approach for dissecting the complexity of the immune system at the single-cell level. This technique enables detailed analysis of B and T cell receptor rearrangements, showing substantial potential in vaccine development, immunotherapy design, and in vitro diagnostics. By evaluating immune responses to various pathogens, researchers can identify effective antigen targets, facilitating the advancement of novel vaccines. Moreover, tracking immune cell dyn......
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• Single-Cell Exome Sequencing
Single-cell exome sequencing technology is designed to investigate gene expression differences at the single-cell level. The exome encompasses the genome's protein-coding regions, which are vital for cellular functions. Through single-cell exome sequencing, researchers can precisely examine the gene-level distinctions among various cell types, shedding light on the differential functional characteristics inherent to each cell. In cancer research, this technology can pinpoint rare but lethal oncogenic ......
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• Single-Cell DNA Methylation Sequencing
Single-cell DNA methylation sequencing is instrumental in analyzing DNA methylation patterns in individual cells. DNA methylation, a pivotal epigenetic modification, involves the addition of methyl groups primarily at cytosine bases within the DNA sequence. This modification impacts gene expression without altering the DNA sequence, playing vital roles in gene regulation, cellular development, and differentiation. Abnormal methylation patterns are closely linked to various diseases, particularly cance......
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• Long-Read Single-Cell Sequencing
Long-read single-cell sequencing, which integrates long-read sequencing with single-cell analysis, has emerged as a powerful tool for dissecting complex biological questions. This technique has demonstrated significant potential across various research domains. In cancer research, long-read single-cell sequencing provides precise identification and localization of structural variations and point mutations within the genome. By delivering high-resolution genome maps, it facilitates a deeper understandi......
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• Mouse Liver Single Cell RNA Seq
Mouse liver single cell RNA sequencing technology specializes in the analysis of RNA expression at the single-cell level within the mouse liver. This method reveals the gene expression profiles and functional states of various cell types. By resolving the heterogeneity inherent in biological samples, it serves as a powerful tool for investigating the biological characteristics of the liver, mechanisms of diseases, and drug effects. The liver, as a complex organ, performs essential physiological functi......
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• Mouse Lung Single-Cell RNA Seq
Mouse lung single-cell RNA sequencing is an advanced genomics technology designed to analyze gene expression at the single-cell level in mouse lung tissue. This approach unveils cellular differences and interactions, providing crucial insights into the physiological functions and pathological modifications of the mouse lung. The lung is a complex organ comprising various cell types, such as epithelial, stromal, and immune cells, each contributing uniquely to its development, maintenance, and disease p......
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• Structure-Based Drug Discovery
Structure-based drug discovery is an approach that leverages the three-dimensional structural information of biomacromolecules to guide and advance new drug development. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR), and cryo-electron microscopy provide high-resolution protein conformations, enabling researchers to comprehend protein functions and their interactions with ligands. This approach not only accelerates the drug design process but also improves the precision and......
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