Resources

Proteomics Databases



Metabolomics Databases

• • Empowering Discoveries: Unlocking the Potential of Targeted Proteomics Analysis with MtoZ Biolabs

  MtoZ Biolabs, a leader in proteomics services, provides targeted proteomics analysis for researchers in biochemistry, biotechnology, and biopharmaceuticals. Our services include MRM and PRM quantitative proteomics, as well as AQUA analysis, supporting the study of post-translational modifications, protein conformations, interactions, kinetics, and metabolic and signaling pathways.

• • De Novo Protein Sequencing Service at MtoZ Biolabs: Unlocking Protein Functions

  Accurate determination of protein sequences plays a crucial role in the development of commercial monoclonal antibodies, vaccines, and assay kits. MtoZ Biolabs's innovative de novo protein sequencing platform for protein analysis, leveraging the high-resolution mass spectrometer Orbitrap Fusion Lumos and extensive bioinformatics expertise.

• • MtoZ Biolabs: Your Partner for Advanced Protein Sequencing and Analytical Services

  MtoZ Biolabs is an integrated CRO specializing in cutting-edge proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis. We are excited to introduce our protein full-length sequencing service, specifically designed to support researchers in the fields of biochemistry, biotechnology, and biopharmaceuticals.

• • Protein Sequencing Service by Edman Degradation Analysis

  MtoZ Biolabs utilizes the SHIMADZU PPSQ-33A analyzer to provide Protein sequencing service by Edman degradation. Samples include but are not limited to purified protein products, antibodies, and protein vaccines, etc. Using our sequencing system, the sequence information of the 30 amino acids at the N-terminus can be determined. Using a specific protein loading system, the 60-70 amino acids at the N-terminus can be determined.

• • MtoZ Biolabs Announces Advanced C-Terminal Sequencing Service for Biochemical Research

  MtoZ Biolabs offers state-of-the-art C-terminal sequencing service utilizing LC-MS/MS technology, ensuring high sensitivity and specificity while maintaining compliance with ICH Q6B regulatory guidelines. Our one-stop service provides customized experimental protocols, detailed data reports and accurate C-terminal amino acid sequence information to support the research and development of various biological products.

• • MtoZ Biolabs Advanced N-Terminal Sequencing Service

  The N-terminal of a protein marks the beginning of its expression and is integral to regulating subcellular localization, degradation, and turnover. MtoZ Biolabs offers high-quality N-terminal sequencing service through an advanced platform that integrates Edman degradation with mass spectrometry, which is suitable for a variety of sample types, including but not limited to proteins, peptides, antibodies, vaccines, recombinant proteins, etc.

• • Methods for Detecting Protein Disulfide Bonds

  Protein is an important functional molecule in organisms, and its structure and function are influenced by disulfide bonds. Disulfide bonds are covalent bonds between two cysteine residues and play a crucial role in protein stability and structure. Therefore, accurate detection and quantification of disulfide bonds in proteins are key issues in biopharmaceutical research and quality control.

• • Mechanisms of Protein Disulfide Bond Analysis in Cell Signaling

  A disulfide bond is a special type of chemical bond formed between two sulfur atoms. In biological organisms, proteins are typically composed of amino acids, with cysteine being the only amino acid that contains a sulfur atom. When the sulfur atoms of two cysteine residues undergo an oxidation reaction, they form a disulfide bond. The formation of disulfide bonds can stabilize the structure of proteins and ensure their normal function.

• • Application and Advantages of Omics Technologies in Post-Translational Modification Identification

  Transcriptional post-transcriptional modification refers to the chemical modification process that RNA molecules undergo during gene transcription. These modifications can affect the stability, transport, translation, and function of RNA, playing an important regulatory role in cellular physiological processes.

• • Diversity in Regulation of Tissue Protein Phosphorylation

  Protein phosphorylation is the most common post-translational modification in cells, and it regulates the structure, function, and interactions of proteins. Protein phosphorylation plays an important regulatory role in biological processes such as cell signaling, metabolism regulation, and cell cycle. The diversity of tissue-specific protein phosphorylation regulation has made it a hot topic in the field of biopharmaceutical research.