Resources

Proteomics Databases



Metabolomics Databases

• • Workflow of Parallel Reaction Monitoring

  Parallel reaction monitoring is an innovative experimental technique widely applied in chemical and biological research. This method allows for the real-time monitoring of multiple reactions under the same experimental conditions, significantly enhancing experimental efficiency and data reliability.

• • Application of Parallel Reaction Monitoring

  Parallel Reaction Monitoring (PRM) is a highly sensitive quantitative mass spectrometry technique widely used in biological and medical research. Its primary advantage lies in the ability to simultaneously monitor multiple target compounds, significantly enhancing analytical efficiency and data reliability.

• • Advantages and Disadvantages of Parallel Reaction Monitoring

  Parallel Reaction Monitoring (PRM) is a highly sensitive and specific mass spectrometry technique widely used in biology, drug development, and clinical research. It significantly enhances analytical efficiency by simultaneously monitoring multiple target analytes. However, despite its numerous advantages, PRM also faces several challenges in practical applications.

• • Principle of Parallel Reaction Monitoring

  Parallel Reaction Monitoring (PRM) is an advanced mass spectrometry technique widely used in biomedical research to monitor the dynamic changes of specific molecules. The key aspect of this technology lies in its ability to simultaneously monitor multiple reactions rather than tracking each reaction individually, thereby enhancing analysis efficiency and accuracy.

• • Interpretation of Secondary Structure Changes in ADC Drugs

  ADC drugs, also known as Antibody-Drug Conjugates, are a novel type of targeted therapeutic drugs. They connect highly selective antibodies with powerful cytotoxic drugs through stable linkers, retaining the targeting ability of antibodies while possessing the killing power of drugs, making them an ideal "smart bomb".

• • Amino Acid Analysis Methods for Protein Diversity Studies

  Amino acids are the fundamental building blocks of proteins, and their composition and sequence determine the structure and function of proteins. Therefore, the analysis of amino acids is of great significance for understanding the diversity of proteins.

• • Sample Preparation in Amino Acid Analysis

  Amino acid analysis is an important technique in the field of biopharmaceuticals, and it has significant implications for drug development, production, and quality control. However, the accuracy and reliability of amino acid analysis largely depend on the quality of sample preparation.

• • PI Detector Unveiling the Mystery of Protein Conformation

  In the microscopic realm of the biological world, our eyes cannot directly see proteins. Proteins, like numerous "chemical workers," are involved in complex biochemical reactions within our bodies. However, did you know that these "chemical workers" are diverse and their behavior in our bodies is equivalent to charges in an electric field? Technically, this is referred to as the isoelectric point or pI value.

• • Amino Acid Composition Analysis for Protein Helical Structure Identification

  Amino acid composition analysis (also known as amino acid quantification analysis) is a technique that involves hydrolyzing, eluting, and detecting amino acids in a biological sample using methods such as high-performance liquid chromatography or capillary electrophoresis. The analysis provides information on the content and ratio of each amino acid, which can be used to understand the nature, function, and stability of protein samples.

• • Purity and Size Analysis of Inactivated Vaccine Virus Particles

  Inactivated vaccines refer to vaccines made by culturing and inactivating pathogenic microorganisms, and they are a common type of vaccines. For viral inactivated vaccines, viral structural proteins are one of the most important components, including surface proteins and capsid proteins. Viral structural proteins are critical factors in the virus life cycle and host infection, and they are also the main target for immune response triggered by vaccines.