Resources

Proteomics Databases



Metabolomics Databases

• • MS-Based Polyclonal Antibody Sequencing vs. BCR-Seq: Which Strategy Fits Your Antibody Discovery Project?

  Compare MS-based polyclonal antibody sequencing and BCR-seq for antibody discovery, covering sample input, repertoire depth, protein-level confirmation, and strategy selection by project goal.

• • Proteomics Service for Protein Identification, Quantification, and PTM Profiling

  A practical guide to proteomics services covering protein identification, quantification, and PTM profiling, with selection criteria and next steps for project planning.

• • Why Polyclonal Antibody Sequencing Is Challenging: Mixture Complexity, Low-Abundance Clones, and CDR Coverage Gaps

  Learn why polyclonal antibody sequencing is challenging due to mixture complexity, low-abundance clone loss, and CDR coverage gaps, and how enrichment and layered MS improve resolution.

• • Protein Mass Spectrometry Facility

  A practical guide to protein mass spectrometry facilities covering capability areas, selection criteria, facility types, and next steps for protein and biologics sample projects.

• • Planning a Native MS Project: What to Confirm Before Submitting Protein Complex or Biologics Samples

  A practical planning guide to what to confirm before submitting protein complex or biologics samples for native MS, covering question framing, buffer, purity, partners, and shipping.

• • Polyclonal Antibody Sequencing: How Complex Antibody Mixtures Can Be Resolved by MS-Based and Sequence-Guided Analysis

  Learn how complex polyclonal antibody mixtures are resolved by MS-based de novo analysis and sequence-guided contig assembly, including deconvolution workflow, mass constraints, and reporting outputs.

• • Polyclonal Antibody Sequencing Technology and Applications

  Explore polyclonal antibody sequencing technology including LC-MS/MS, de novo sequencing, middle-down analysis, and intact mass profiling, and their applications in research, diagnostics, and biopharma.

• • Why Native MS Experiments Fail: Buffer, Stability, and Complex Preservation Issues to Check Before Analysis

  A troubleshooting guide to why native MS experiments fail, covering buffer compatibility, protein stability, complex preservation, and a pre-analysis checklist.

• • What is Polyclonal Antibody Sequencing?

  Learn what polyclonal antibody sequencing is, how it differs from monoclonal sequencing, what outputs it produces, and when mass spectrometry is used to characterize polyclonal IgG.

• • Native MS: How Non-Denaturing Mass Spectrometry Reveals Protein Complexes, Stoichiometry, and Binding States

  A technical guide explaining how non-denaturing native mass spectrometry reveals protein complexes, stoichiometry, and binding states for intact protein and biologics characterization.