Resources

Proteomics Databases



Metabolomics Databases

• • Principle of Cell Surface Proteomics

  Cell surface proteomics is a critical field that studies the proteins on the surface of cell membranes and their functions. These proteins play vital roles in intercellular signaling, cell recognition, immune responses, and other biological processes.

• • Application of Exosome Proteomics

  Exosomes are small membrane vesicles secreted by various cells, typically ranging from 30 to 150 nanometers in diameter. They play crucial roles in intercellular communication, material transport, and cell signaling. As research into exosome biology deepens, exosome proteomics has emerged as a burgeoning field, increasingly demonstrating its potential applications in biomedical research, disease diagnosis, and treatment.

• • Workflow of Exosome Proteomics

  Exosomes are small membrane vesicles secreted by cells, containing a variety of biomolecules such as proteins, lipids, and RNAs. In recent years, the significance of exosomes in intercellular communication, disease diagnosis, and therapy has become increasingly prominent, making exosome proteomics research vital.

• • Application of Subcellular Proteomics

  Subcellular proteomics is the study of the protein composition within different subcellular compartments, such as the nucleus, cytoplasm, and mitochondria. With advancements in technology, subcellular proteomics is increasingly demonstrating its significance in both basic research and clinical applications.

• • Mechanism of Subcellular Proteomics

  Subcellular proteomics is a crucial field dedicated to studying the composition and functions of protein groups in different subcellular compartments. With the advancement of high-throughput proteomics technologies, researchers can delve into the dynamic changes and interactions of proteins within cells, revealing the complexity and diversity of cellular functions.

• • Workflow of Subcellular Proteomics

  Subcellular proteomics is a crucial field for studying protein expression and function in various subcellular compartments. With technological advancements, methods in subcellular proteomics have diversified, particularly in quantitative analysis and functional studies. The following outlines the workflow of subcellular proteomics, aiming to provide researchers with a clear guide.

• • Mechanism of Proteomic Analysis in FFPE Samples

  Formalin-fixed, paraffin-embedded (FFPE) samples are among the most commonly used specimen types in modern pathology. This process preserves cellular morphology and structure by fixing biological samples in formalin and subsequently embedding them in paraffin. The advantages of FFPE samples include long-term storage and reversibility, offering significant application potential in cancer research, genetic studies, and drug development.

• • Workflow of FFPE-Based Proteomic Analysis

  Formalin-fixed paraffin-embedded (FFPE) samples are widely used in clinical and research settings due to their importance in tissue preservation and long-term storage. Proteomic analysis of FFPE samples can provide crucial insights into tumor biology, disease mechanisms, and potential therapeutic targets.

• • Application of FFPE Proteomics in Disease Research

  Formalin-fixed paraffin-embedded (FFPE) samples are commonly used materials in medical research, widely applied in tissue pathology, clinical diagnostics, and biomarker development. Due to their ease of long-term preservation and large-scale collection, FFPE samples provide a valuable resource for disease research. With advancements in proteomics technologies, the analysis of protein profiles from FFPE samples has become an essential tool for uncovering disease mechanisms.

• • Principle of Proteomics in Paraffin Embedded Samples

  Paraffin-embedded tissue proteomics is an essential technique for analyzing the protein composition and expression in tissue samples. The core principle involves the processing of biological samples (such as tumor tissues or other pathological tissues) through fixation, dehydration, and embedding steps, facilitating subsequent mass spectrometry analysis. This technique not only preserves the morphological structure of samples but also provides higher resolution and sensitivity in analyses.