Resources

Proteomics Databases



Metabolomics Databases

• • Spatial Proteomics Metal Tag

  Spatial Proteomics with Metal Tags is an advanced method that combines mass spectrometry and bioimaging technologies to study the spatial distribution and function of proteins at the tissue or cellular level. This technique involves labeling proteins with heavy metal ions, followed by imaging using Laser Ablation Mass Spectrometry Imaging (LA-MSI) or similar techniques. It enables precise analysis and visualization of protein distribution in biological tissues without damaging the samples.

• • Chemical Proteomics and Drug Target Discovery

  Chemical proteomics is a research approach that combines chemistry, biochemistry, and proteomics techniques. It is primarily used to study the interactions between proteins and small molecules, thereby revealing the functions and regulatory mechanisms of proteins, as well as their roles in diseases. The main steps include:

• • How to Identify Differences Between Two Groups of Proteins Through Proteomics Research

  The main steps involved in identifying differences between two groups of proteins through proteomics research include the following: Sample Preparation: Select two or more different conditions or sample groups (e.g., disease group and control group). Extract proteins and conduct necessary processing, such as protein concentration measurement and normalization. Protein Separation and Identification: Two-dimensional gel electrophoresis (2-DE) is a traditional protein separation technique that achieves......

• • Protein Chemistry and Proteomics

  Protein chemistry and proteomics are two important fields that study biomolecules, particularly proteins. They explore the structure, function, and interactions of proteins from different perspectives, providing a foundation for understanding biological processes and disease mechanisms. Although these fields are closely related, they differ in their focus and the technical methods they use.

• • Antibody-Drug Conjugate Analysis

  Antibody-Drug Conjugate Analysis refers to the process of in-depth study and evaluation of the structure, composition, and characteristics of antibody-drug conjugates (ADCs). ADCs represent a novel class of biotherapeutic agents that combine cytotoxic drugs with specific antibodies, enabling targeted delivery of the drug to cancer cells and achieving efficient tumor-killing effects. This strategy not only enhances the therapeutic index but also minimizes toxicity to healthy cells. The primary objectiv......

• • Antibody Sequencing Service for Drug Development

  Antibody Sequencing Service refers to the process of determining the amino acid sequence of an antibody through high-precision mass spectrometry analysis and bioinformatics techniques. Antibodies are critical molecules of the immune system, playing an essential role in defending against pathogens by recognizing and binding to specific antigens. Antibody sequencing services have wide-ranging applications in the biopharmaceutical field, including but not limited to antibody drug development, antibody en......

• • 2D-DIGE Proteomics

  2D-DIGE proteomics, or two-dimensional difference gel electrophoresis proteomics, is a high-resolution protein separation technique derived from traditional two-dimensional gel electrophoresis (2-DE). By combining fluorescence dye labeling, it allows for the simultaneous analysis of multiple samples. In 2D-DIGE, protein mixtures are separated via isoelectric focusing and SDS-PAGE, enabling both resolution and quantification of samples on the same gel. This technique uniquely labels samples with differ......

• • Antibiotic Identification

  Antibiotic identification refers to the scientific techniques used to detect and confirm the types and characteristics of antibiotics. Antibiotics are secondary metabolites produced by microorganisms (such as bacteria and fungi) that can inhibit or kill other microorganisms. They are extensively used in both medical and agricultural applications. Antibiotics encompass a wide range of compounds, including penicillins, cephalosporins, aminoglycosides, and tetracyclines, each with distinct mechanisms of ......

• • SDS-PAGE Analysis of Proteins

  SDS-PAGE analysis of proteins is a widely employed technique in biochemical and molecular biology research, designed for separating and analyzing individual proteins within complex mixtures. SDS-PAGE, which stands for Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis, leverages the denaturing properties of SDS (Sodium Dodecyl Sulfate) and the resolving power of polyacrylamide gels to separate proteins based on their molecular weight. SDS, an anionic detergent, binds uniformly to proteins, mask......

• • SDS-PAGE Protein Separation

  SDS-PAGE protein separation is a widely utilized electrophoretic technique in proteomics, enabling the separation of proteins based on their molecular weight. SDS, or Sodium Dodecyl Sulfate, is an anionic detergent that denatures proteins by disrupting their secondary and tertiary structures, ensuring uniform linear migration during electrophoresis. PAGE, short for Polyacrylamide Gel Electrophoresis, employs a gel matrix to facilitate size-based separation. In this method, protein samples are treated ......