Resources

• • Phosphoproteomics Deciphering the Phosphorylation Regulatory Mechanisms of Cell Signaling Transduction

  Cell signaling is an important process for maintaining cellular activities, regulating the physiological functions of cells through a series of signaling molecules and pathways. Among them, phosphorylation regulation mechanism plays a crucial role in cell signaling. Phosphorylation refers to the addition of phosphate groups (phosphorylation groups) to protein molecules, thereby altering their structure and function.

• • Phosphoproteomics Revealing Links Between Protein Degradation and Cell Function

  Cells are the basic units of life, and their normal functioning is crucial for maintaining the normal physiological activities of an organism. Proteins, as important components of cells, participate in almost all cellular regulatory processes. Phosphorylation is a common protein modification method, and through phosphorylation, the structure and function of proteins can be altered, thereby affecting important physiological processes such as cell signaling, metabolic regulation, and cell cycle.

• • How Does Phosphorylation Modulate Protein Folding and Redox Linkages?

  Protein is one of the most important molecules in living organisms and plays various functions within cells. However, the function of proteins is often regulated by their structure. Phosphorylation modification, as a common protein modification, plays an important role in regulating protein folding and redox processes.

• • Differences Between Glycosylation Modification and Identification in Research Focus and Method Selection

  In organisms, proteins are not only the most important functional molecules in cells, but also play crucial roles in various biological processes and signaling pathways. To enhance the functionality and diversity of proteins, cells undergo various modifications of proteins, among which glycosylation has received significant attention as an important protein modification.

• • Prospects of Phosphorylation Modifications in Drug Development

  With in-depth research on protein modifications, phosphorylation modification plays a crucial role in cellular regulation as an important signaling transduction mechanism. In recent years, phosphoproteomics analysis has gradually become a hot topic in drug development.

• • Glycan Profiling Facilitating Analysis of Protein-Glycan Interactions

  Glycan profiling, as one of the important techniques in the field of glycomics for biopharmaceuticals, is becoming a critical step in drug development. Many proteins on the cell surface and within cells undergo covalent attachment with glycans, forming glycosylation modifications. This type of modification not only regulates protein structure and function, but also has important effects on the stability, activity, and immunogenicity of biopharmaceuticals.

• • Modified Proteomics Revealing Protein-Modification Relationships

  Protein is the most diverse biomolecule in cells, and the diversity of its structure and function is often closely related to its modification state. As an important branch of the field of phosphoproteomics, modified protein proteomics aims to study various types of protein modifications in order to comprehensively understand the relationship between proteins and modifications.

• • Breakthroughs in Proteomics Research Revealing Biomarker Potential and Mechanisms

  Biomarkers are molecular features that can be used to indicate the physiological state, disease progression, and prognosis of an organism. Revealing and utilizing biomarkers is of great significance in biopharmaceutical research. Proteomics, as a discipline that studies the composition, structure, function, and interactions of all proteins within an organism, provides rich methods and technologies for discovering and studying biomarkers.

• • How to Establish Sample Submission Standards for Peptide Identification?

  In the field of biomedicine, obtaining accurate and reliable experimental results and data requires the correct experimental methods, and in this process, sample handling is a crucial step. The establishment of sample submission criteria suitable for peptide identification is a fundamental link that affects the accuracy of experimental results.

• • Proteomics Analysis of Biological Samples

  Proteomics is a scientific field that studies the composition, structure, function, and interactions of all proteins within an organism. With the continuous development of technology, proteomics has been widely applied in the field of biomedicine. Among them, proteomics analysis of biological samples is an important means to deeply explore proteomic information.