Resources

• • What Advanced Techniques are Used for Absolute Quantification in Proteomics?

  One important direction in proteomics research is the quantitative analysis of proteins. Traditional relative quantification methods provide information on the relative abundance of proteins but cannot accurately measure the absolute abundance of proteins. To overcome this limitation, researchers have developed many advanced techniques for absolute quantification analysis in proteomics.

• • Standards for Screening Differential Proteins in Proteomics

  Proteomics is the scientific field that studies the composition, structure, function, and interactions of all proteins in an organism. With the continuous development of technology, proteomics is being widely applied in the field of biomedicine. Among them, the screening of differentially expressed proteins is an important step in the development of biological drugs. It can help us identify proteins associated with diseases and gain a deeper understanding of the molecular mechanisms of diseases.

• • What Common Qualitative Methods are Used for Protein Identification?

  Protein is an essential functional molecule in living organisms, and its identification and qualification are crucial for understanding the functions and mechanisms of biological systems. Protein qualification refers to determining the presence and properties of proteins, which involves many common qualitative methods.

• • Exploring Potential Biomarkers for Glycan-Related Diseases

  Glycoproteins are a class of proteins tightly bound to sugar molecules. They are widely present on the cell surface and extracellular matrix, and participate in various cellular processes, such as cell-cell interactions, signal transduction, extracellular matrix organization, and inflammation reactions. In recent years, with the continuous development of proteomics technologies, glycoproteomics has emerged as an important branch of proteomics.

• • How to Select the Optimal Mass Spectrometry Technique for Proteomics?

  Proteomics based on mass spectrometry is an important biological research method that helps scientists understand the structure, function, and interactions of proteins by analyzing proteins in biological samples. This in turn promotes the development of biopharmaceutical research and clinical applications. However, when choosing the appropriate mass spectrometry techniques and strategies, researchers need to consider several factors to ensure the accuracy and reliability of the data.

• • Peptidomics Revealing the Composition and Functions of Peptides Within Organisms

  In organisms, peptides are a class of small molecular chains composed of amino acids. Peptides play important functional roles in biology, participating in processes such as regulating cell signaling, metabolic regulation, and antimicrobial defense. However, traditional research methods have limited abilities to comprehensively understand the composition and function of peptides.

• • Analyzing the Spatial Distribution of Proteins in Cells and Tissues Through Spatial Proteomics Technology

  In organisms, proteins serve as the fundamental executors of cellular functions and play important roles in signal transmission, catalysis, and maintenance of structures. However, the functionality of proteins is closely related to their spatial location within cells and tissues. In order to deepen our understanding of the functionality and disease mechanisms of biological systems, as well as to advance the development of biopharmaceuticals, scientists have proposed spatial proteomics techniques.

• • What are the Common Methods for Peptidomics Analysis?

  Peptidomics is the field that studies the complete set of peptides and their functions in organisms. In order to gain a deeper understanding of the composition and functions of peptides in biological systems, scientists have developed various methods for peptidomics analysis. This article will introduce commonly used methods for peptidomics analysis, allowing readers to understand the principles and applications of these methods.

• • Common Methods and Detection Techniques for Interacting Protein Screening

  In the field of biopharmaceuticals, protein-protein interaction is a crucial step in studying biological processes and developing drugs. Protein-protein interaction screening is an important technique used to discover and study the interactions between proteins.

• • Methods for Molecular Weight Determination

  Molecular weight is an important parameter for describing the size of molecules and holds significant significance in the field of biopharmaceutical research and applications. Scientists have developed various methods for measuring molecular weight accurately to determine the mass or size of molecules. This article will introduce the working principles of molecular weight determination methods to help readers understand the basic principles and application scope of these methods.