Resources

• • How to Analyze IP Mass Spectrometry Results?

  IP-MS (Immunoprecipitation Mass Spectrometry), as an interdisciplinary research technique that encompasses biochemistry, molecular biology, and mass spectrometry, is widely used in the field of biomedical research. It enables the study of protein co-precipitation and protein-protein interactions, ultimately advancing the progress of drug development.

• • Can Mass Spectrometry-Based Proteomics Study Peptide Structure and Function?

  Proteins are important biomolecules in living organisms and they are involved in almost all cellular activities. Peptides are important components of proteins and play crucial roles in signal transduction, immune regulation, drug action, and more. Understanding the structure and function of peptides is essential for research in the field of biopharmaceuticals and drug development.

• • Label-Free Quantitative Proteomics Technique

  Proteomics is the field that studies the overall composition and expression of proteins in biological organisms, and it is of great significance for understanding biological processes and disease development. Non-labeled quantitative proteomics technology is a high-throughput and highly sensitive analytical method that can compare the relative abundance of proteins in samples without labeled molecules.

• • Spatial Proteomics of Tuberculosis Revealing Molecular Mechanisms of Pulmonary Lesions

  Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis and poses a serious threat to global public health. Despite the availability of numerous anti-tuberculosis drugs and vaccines, the complex pathogenesis of tuberculosis makes it difficult to eradicate. In recent years, spatial proteomics of tuberculosis has emerged as a novel technique, providing new insights into the molecular mechanisms of pulmonary tuberculosis lesions.

• • Advances and Perspectives of High-Throughput Proteomics in Clinical Research

  With the rapid development of biotechnology, high-throughput proteomics technology is playing an increasingly important role in the field of biomedical research. The emergence of this technology provides scientists with a more comprehensive and efficient means to study protein changes in physiological and disease states.

• • How Does Protein Mass Spectrometry Help in Deciphering Complex Protein Composition?

  The complexity of proteins often makes their analysis and resolution difficult. Fortunately, protein mass spectrometry provides an effective method for resolving complex protein compositions. It is a technique that converts protein molecules into ions for mass analysis. It is based on the principle of mass spectrometry, by converting a protein sample into ions and measuring its mass-to-charge ratio (m/z), thus obtaining the mass spectrum of the protein.

• • Spatial Proteomics Revealing the Spatial Architecture of Biological Systems

  In the magnificent stage of biological science, proteins undoubtedly play one of the most important roles. They are the fundamental biomolecules in organisms and carry out the majority of cellular functions and tasks. However, understanding only the sequence of proteins is not sufficient to reveal their true functions, as protein function is often closely related to their three-dimensional spatial structure.

• • Exploring the Application and Breakthroughs of New Technologies in Protein Purity Identification

  The application and breakthrough of new technologies in protein purity identification provide broad prospects for biological research and clinical applications. By introducing more accurate, high-throughput, and high-sensitivity new technologies, we can better evaluate protein purity and ensure the quality and safety of biological products.   Protein purity is one of the essential indicators of the quality of biological products, and is crucial for ensuring the safety and efficacy of drugs. In recent ......

• • Circular Dichroism Spectroscopy Identification: Determine Whether Proteins Have Helical Structures

  In the study of protein structure, accurately determining whether a protein has a helical structure is one of the key tasks. Circular dichroism spectroscopy identification, as a commonly used technique, can provide important information about the secondary structure of proteins. We will introduce in detail the identification method of CD spectroscopy, focusing on how to use CD spectroscopy analysis to determine whether a protein has a helical structure.

• • Exosome Protein Sequencing: Exploring a New Direction for Intercellular Communication

  Through exosomal protein sequencing, we can gain a deep understanding of the mechanisms and biological functions of intercellular information transfer. Exosomes play a crucial role in the intricate network of intercellular communication. Exosomes are a type of extracellular vesicle released by cells, containing a rich supply of proteins, nucleic acids, and other biomolecules.    Importance of Exosomal Proteins Exosomal proteins are a major component of exosomes and act as messengers in intercellular c......