Resources
Proteomics Databases
Metabolomics Databases
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• Mechanism of N-glycan Analysis Using HILIC-UHPLC
N-glycosylation is a crucial post-translational modification of proteins, widely present in eukaryotic cells. It plays an important role in various biological processes, such as protein folding, stability, cell recognition, and signal transduction. Therefore, accurate analysis of protein N-glycosylation is essential for understanding many biological phenomena and disease mechanisms. N-glycan analysis involves the separation, identification, and quantification of glycan structures.
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• Protein Amino Acid Composition Analysis: Methodology and Practice
Protein is one of the most important molecules in living organisms and plays a critical role in the structure and function of cells. Understanding the amino acid composition of proteins is crucial for understanding their function and structure.
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• Practical Guide to Monosaccharide Composition Analysis: Enhancing Sample Analysis Efficiency
Monosaccharides are the basic units that make up polysaccharides and are of great importance in the field of biopharmaceutical research and development. Monosaccharide composition analysis is a key technique that can help scientists understand the structure and characteristics of polysaccharides. However, traditional methods for monosaccharide composition analysis suffer from low efficiency.
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• IR Spectrum Analysis Steps: Decoding Information from Spectra to Compounds
Infrared spectroscopy is a commonly used analytical tool that helps scientists determine the structure and functionality of compounds. By analyzing an infrared spectrum, we can understand the presence and types of functional groups and chemical bonds in a compound.
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• IR Spectral Analysis Principles: Revealing Information from Spectra to Structure
Infrared spectroscopy is a commonly used analysis technique that provides information about the structure and chemical composition of a sample by measuring its absorption and scattering of infrared light.
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Protein is one of the most crucial molecules in living organisms, playing a key role in the structure and function of cells. The function of proteins is often closely related to their folding state, which is influenced by the secondary structure of peptides.
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• Introduction to Host Cell Protein Isoelectric Point Analysis
Host Cell Protein (HCP) refers to impurity proteins that are unrelated to the target protein and expressed by the host cells during the biopharmaceutical manufacturing process. These HCPs can potentially affect the quality, safety, and efficacy of the drug, making the analysis and control of HCPs crucial in the development and production of biologics.
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• Best Practices: Exploring Sample Range for Host Cell Protein Detection
Host protein detection is an important part of the biopharmaceutical development process, which can help us evaluate the residual host protein content in the host cells of biopharmaceutical formulations. Host proteins refer to proteins produced in host cells during the production process of biopharmaceuticals that are different from the target protein.
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• Peptide Mapping: Analyzing From the Curve to Charge Information
Peptide graph analysis is a method used to study peptide molecules in organisms. By analyzing the peptide graph, we can understand important information about the structure, function, and interactions of peptide molecules.
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• New Insights in Epitope Analysis: Diversity and Mutation Interpretation
Antigenic epitope analysis is an important research direction in the field of biopharmaceuticals, focusing on the interaction between antibodies and antigens. By studying antigenic epitopes in depth, we can better understand the workings of the immune system and provide important guidance for drug development.
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