Resources

• • Acetylation Proteomics and Acetylation Site Analysis

  Proteomics, as an important part of biopharmaceutical research, reveals the complete profile and functions of proteins. One crucial post-translational modification in this field is acetylation, which plays a vital role in cellular processes such as signal transduction and transcriptional regulation.

• • Exploring the Relationship Between Acetylation and Cellular Function

  Acetylation proteomics is a highly regarded research direction in the field of biopharmaceutical proteinomics. Protein acetylation modification, as an important post-transcriptional modification, plays a key role in cellular functional regulation. This article will delve into the functions of acetylated proteins and their close relationship with cellular functions, showcasing the research value and application prospects of acetylation proteomics in the field of biopharmaceuticals.

• • Guide to Acetylated Protein Detection Methods

  Acetylated proteins are important biomolecules that play critical roles in cells. Acetylation is a common protein modification that regulates cellular functions and gene expression by adding acetyl groups to proteins. Understanding acetylation modification is crucial in the development and production of protein drugs in the field of biopharmaceuticals.

• • Analysis Methods and Practical Insights for Glycosylation Sites in Modified Proteomics

  Glycosylation is one of the important protein modifications and plays a key role in cellular functions and regulation. Glycosylation modification is involved in biological processes such as cell signaling, molecular recognition, and immune response, and has significant effects on the structure and function of proteins. In the field of modified proteomics, the analysis of glycosylation sites is a crucial step in understanding the function of glycosylation modifications.

• • Absolute Quantification in Targeted Proteomics

  Targeted proteomics is one of the critical technological approaches in modern biological research, utilizing mass spectrometry (MS) to quantify specific proteins or protein groups. Unlike discovery-based studies in traditional proteomics, targeted proteomics focuses on the precise measurement of known proteins, enabling deeper insights into their biological functions and clinical applications.

• • Protein Interaction Analysis Using Bioinformatic Methods

  Proteins, as fundamental molecules of life, participate in nearly all processes within living organisms, executing functions and transmitting information. Protein-protein interactions (PPIs) are at the core of various biological processes such as signal transduction, metabolic regulation, and cell cycle control. Therefore, elucidating the interactions between proteins is critical for understanding biological functional networks, disease mechanisms, and drug target development.

• • PRM-Based Analysis of Targeted Proteomics

  Targeted proteomics is a critical approach for protein research, enabling the quantification of specific proteins or peptides. This technology plays a significant role in studying changes in protein expression and mechanisms within complex samples. Among various targeted proteomics methods, Parallel Reaction Monitoring (PRM) has gained attention due to its high sensitivity, specificity, and throughput.

• • Detection Steps in Cellular Proteomics Using Liquid Chromatography

  Proteomics is a crucial field that studies all proteins and their interactions within a cell, tissue, or organism. Liquid Chromatography (LC) combined with Mass Spectrometry (MS) is one of the core techniques in proteomics research, particularly suitable for the efficient separation and identification of proteins in complex samples.

• • Glycated Albumin Measurement and High-Performance Liquid Chromatography

  Glycated albumin is a type of biomarker that is of significant importance in the diagnosis and monitoring of diabetes and other chronic diseases. Its measurement is crucial for understanding disease progression and evaluating treatment effectiveness. In the field of biopharmaceuticals, high-performance liquid chromatography (HPLC) has become a commonly used and effective method for the determination of glycated albumin.

• • Deciphering the Mechanisms of Histone Modification

  Proteomics of post-translational modifications (PTMs) is a scientific field that studies the expression, structure, and function of proteins within organisms. In biology, protein modifications are crucial mechanisms for cellular regulation and signal transduction. PTM proteomics analysis is an emerging technique that reveals the important roles of protein modifications in cellular processes through high-throughput analysis of histone modifications.