Resources

• • Mass Cytometry Analysis of Cell Phenotypes

  The world of life is so wonderful, with each organism composed of an astonishing number of cells, and each type of cell having its own unique characteristics and functions. How to observe and understand the heterogeneity, cell phenotypes, and their differences has been a long-standing research direction for biologists. For this purpose, the field of biopharmaceuticals brings us a powerful tool - mass spectrometry flow cytometry technology.

• • Detection of Glycosylation Sites (N-glycan, O-glycan) in Recombinant Protein Vaccines

  Recombinant protein vaccines are a novel type of vaccine product produced using genetic engineering technology in organisms or cell systems. During the production process of these vaccines, glycosylation reactions may occur, where sugar chains are added to the N-site (e.g. asparagine) and O-site (e.g. serine or threonine) of the protein. Glycosylation is an important post-translational modification of proteins that affects their stability, solubility, biological activity, etc.

• • What Proteins Can Astral High-Resolution Mass Spectrometry Detect?

  Astral high-resolution mass spectrometry is a novel technological tool that has been widely used and achieved significant success in the field of biopharmaceuticals. Its main function is to provide protein analysis and accurately lock in protein mass spectrometry data. With its excellent performance, researchers can conduct in-depth studies on various types of proteins, promoting advances in biological science.

• • Determination of Isoelectric Point of Recombinant Protein Drugs

  Recombinant protein drugs refer to protein products derived from animals and plants through biotechnological research and development, which have certain biological activity and can prevent, treat, and diagnose diseases in humans, animals, and plants. Compared to small molecule drugs, recombinant protein drugs have advantages such as high activity, high specificity, and low toxicity, which makes them favored by researchers.

• • Mass Spectrometry Screening Revealing Protein Interaction Network Construction

  Within cells, proteins do not work independently but form a complex network called the protein interactome. These interactions are crucial for maintaining normal cellular functions. Screening for interacting proteins using mass spectrometry technology is like solving a puzzle to unravel this network.

• • Principle of Protein Interaction Network Analysis

  Protein interaction network analysis is a systems biology approach that uses computational and experimental methods to decipher the interactions among proteins within a biological system. Proteins, as executors of cellular functions, play a crucial role in regulating biological processes and maintaining physiological balance.

• • Introduction to Micrometer Protein Mass Spectrometry

  Proteins, as the main components of functional molecules in organisms, play important roles in disease diagnosis, treatment, and drug development. Studying the structure and function of proteins helps uncover mysteries in cell biology, biochemistry, and pharmacology. Protein mass spectrometry, as an efficient and accurate protein analysis technique, has been widely used in scientific research and clinical applications.

• • Principle of COG Functional Annotation Analysis

  COG (Clusters of Orthologous Groups of proteins) is a critical resource for protein functional annotation. It uses orthologous relationships to classify proteins by function, aiding researchers in understanding protein functions within biological and genomics contexts. COG functional annotation analysis is a bioinformatics tool widely employed in genome annotation, comparative genomics, and metabolic pathway analysis.   The COG database, developed by NCBI (National Center for Biotechnology Information......

• • Screening Techniques and Detection Methods for Glycan-Interacting Proteins in Glycome Analysis

  Glycoproteins, as an important class of biomolecules, play crucial roles in processes such as cell signaling, immune response, and cell recognition. The functions of glycoproteins are closely associated with their unique glycosylation structures.

• • Composition and Function of Polypeptides from Enzymatic Hydrolysis of Natural Samples

  Proteins in organisms are usually broken down into peptides through the process of enzymatic digestion, and these peptides play important physiological and biological roles in the organism. However, studying the composition and functions of these peptides in depth is a challenging task. Peptidomics, as an advanced biotechnology, focuses on the in-depth analysis of the composition and functions of peptides in enzymatic digestion products of natural samples.