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    Resources

      Proteomics Databases

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      Metabolomics Databases

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    • • Principle of Gel and IP Sample Protein Identification

      Protein identification is a fundamental aspect of biochemistry and molecular biology, essential for understanding protein structure, function, and interactions. Two widely used techniques for protein identification are gel electrophoresis and immunoprecipitation (IP). These methods offer distinct yet complementary approaches to isolate and analyze proteins, providing invaluable insights into cellular processes and disease mechanisms.

    • • Mechanism of Macromolecular Mass Measurement

      Macromolecular mass measurement is a cornerstone of modern scientific research, essential for elucidating the structure, function, and interactions of large molecules such as proteins, nucleic acids, and synthetic polymers. Accurate measurement of these macromolecules’ mass is critical across various disciplines, including biochemistry, molecular biology, and materials science.

    • • Application of Macromolecular Mass Measurement

      Macromolecular mass measurement is a pivotal technique in modern science, providing invaluable insights into the structure, function, and interactions of large molecules such as proteins, nucleic acids, and synthetic polymers. This article explores the diverse applications of macromolecular mass measurement across various scientific fields, emphasizing its importance in advancing research and development.

    • • Principle of Macromolecular Mass Measurement

      Accurate mass measurement of macromolecules, such as proteins, nucleic acids, and synthetic polymers, is fundamental in biochemistry, molecular biology, and materials science. Understanding the mass of these macromolecules provides insights into their structure, function, and interactions.

    • • Mechanism of Protein Molecular Weight Determination by MS

      Protein molecular weight determination is a cornerstone in the field of proteomics, aiding in the identification and characterization of proteins. Mass spectrometry (MS) has emerged as a pivotal technique for this purpose, offering high sensitivity, accuracy, and speed.

    • • Mechanism of MS-Based Protein Interaction Identification

      Proteins are crucial biomolecules in cells, performing complex biological functions through various interactions. Understanding protein-protein interactions is essential for revealing the mechanisms of biological processes. Recently, mass spectrometry-based protein interaction identification (MSPII) has gained attention due to its high sensitivity, throughput, and precision.

    • • Application of MS-Based Protein Interaction Identification

      Mass spectrometry (MS) is a highly sensitive analytical technique widely employed in proteomics. The identification of protein-protein interactions (PPIs) using mass spectrometry holds a pivotal role in biological research. This article provides a detailed overview of the applications of mass spectrometry in the identification of protein-protein interactions.

    • • Workflow of MS-Based Protein Interaction Identification

      Mass spectrometry (MS) has become a crucial tool in modern proteomics, particularly for identifying protein-protein interactions. MS technology allows for accurate and rapid identification and quantification of dynamic changes in protein interactions. This article provides a detailed overview of the workflow for identifying protein-protein interactions using mass spectrometry, aiding researchers in understanding and applying this technology effectively.

    • • Advantages and Disadvantages of MS-Based Protein Interaction Identification

      Understanding protein-protein interactions is crucial for uncovering complex physiological and pathological processes in organisms. In recent years, mass spectrometry (MS)-based techniques have gradually become the preferred tool for researchers studying these interactions. This article explores the advantages and disadvantages of mass spectrometry-based identification of protein-protein interactions.

    • • Mechanism of Unknown Protein Identification

      With the rapid advancement of genomics and proteomics technologies, many previously unknown proteins have been discovered. However, the functions and mechanisms of these proteins remain largely unexplored. Identifying the mechanisms of unknown proteins is crucial for understanding biological processes, discovering new drug targets, and developing new therapeutic approaches. This article explores the current mechanisms and methods used to identify unknown proteins in detail.

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