Resources

Proteomics Databases



Metabolomics Databases

• • Integrated Exosome Omics Services: Unveiling Cellular Communication and Disease Mechanisms

  Extracting and characterizing exosomes pose specific challenges due to their small size and complex composition. Our service incorporates: 1. Extraction Methods Including ultracentrifugation—the gold standard, polymer precipitation, and cutting-edge TiO2 enrichment for material-specific exosome isolation. 2. Characterization Techniques Adhering to the International Society for Extracellular Vesicles' (ISEV) 2018 guidelines, we employ a range of characterization methods such as electron microscopy, nan

• • Advanced Plant Metabolomics Services: Harnessing LC-MS/MS for Comprehensive Metabolic Profiling

  At MtoZ Biolabs, we specialize in providing cutting-edge plant metabolomics services, utilizing advanced Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) to explore the intricate metabolic networks in plants. Our services are designed to uncover the vast array of metabolites that play crucial roles in plant growth, response to environmental stress, and developmental processes.

• • Advanced 4D Proteomics Services at MtoZ Biolabs

  At MtoZ Biolabs, we are proud to introduce our advanced 4D Proteomics services, designed to cater to the evolving needs of the scientific community. Our state-of-the-art technology leverages the timsTOF Pro system, integrating Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation Serial Fragmentation (PASEF) to deliver unmatched speed and sensitivity in protein analysis.

• • Quantitative Analysis of Protein Lactylation Sites

  Protein lactylation is a post-translational modification in which lactate, produced under anaerobic conditions and accumulated during glycolysis, reacts with lysine residues in proteins, attaching a lactyl group to the lysine residues. This leads to protein lactylation, thereby regulating protein function. This modification plays a significant role in metabolic regulation and cancer biology.

• • Detection of Protein Deamidation Using High-Resolution Mass Spectrometry

  Proteins are the central molecules of life, with their structure and function heavily influenced by specific post-translational modifications (PTMs). Deamidation is one of the most common PTMs, typically occurring at asparagine (Asn) and glutamine (Gln) residues. The occurrence of deamidation can lead to alterations in protein structure and function, affecting protein stability, activity, and interactions with other molecules.

• • Detection of Protein Complexes via 2D Blue Native/SDS-PAGE

  Protein complexes perform various functions within cells, and their dynamic nature and compositional diversity make them crucial subjects of study. Traditional protein separation techniques, such as SDS-PAGE, are effective at separating proteins but often fail to maintain the integrity of protein complexes.

• • Proteomics: Unveiling Scientific Principles

  Proteomics is one of the most important fields of study in biology, focusing on the comprehensive analysis of protein composition, structure, and function in organisms. It plays a crucial role in understanding cellular functions and biological processes.

• • Comparative Analysis of Protein Structure via Co-IP and Pull-Down

  Protein is an important functional molecule in living organisms, and its structure determines its function. Therefore, understanding the structure of proteins is crucial for understanding their function and the biological processes they participate in. In the field of biopharmaceutical research, scientists often use different methods to decipher the structure of proteins. Among them, Co-immunoprecipitation (CO-IP) and Pull Down are two commonly used methods.

• • Comparison of Protein Detection Methods by HPLC

  Protein is an important functional molecule in organisms, and it is of great significance for studying biological processes and developing biopharmaceuticals. Accurate identification methods are required for the study of protein structure and function. Among them, protein HPLC detection method is a commonly used technique.

• • Exploring Mass Spectrometry Software in Peptide Mass Studies

  Peptides are biopolymers composed of amino acids and possess wide-ranging biological activities and pharmacological applications. In the field of biopharmaceuticals, the research and development of peptide drugs have become a hot research direction. Mass spectrometry analysis of peptides is an indispensable part of peptide research.