Resources
Proteomics Databases
Metabolomics Databases
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• Liver Proteomics: Insights into Function and Disease
Liver proteomics is a scientific discipline that employs proteomics technologies to systematically investigate the composition, structure, function, and regulatory mechanisms of proteins in liver tissues. As a crucial metabolic organ in both humans and animals, the liver plays a central role in biochemical processes such as substance metabolism, detoxification, immune regulation, and plasma protein synthesis. Liver proteomics research enables the elucidation of the molecular mechanisms underlying thes......
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Glycosylation analysis is a specialized technique for investigating protein glycosylation, a post-translational modification in which sugar moieties are enzymatically attached to proteins. This modification is widespread and structurally diverse in biological systems, influencing protein conformation, stability, function, and molecular interactions. Glycosylation analysis is critical due to its extensive biological roles and clinical significance, including protein function regulation, cell-cell recog......
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IPA analysis proteomics is an advanced bioinformatics tool designed to interpret complex proteomics data. By mapping mass spectrometry-identified proteins onto established biological networks, signaling pathways, and disease mechanisms, IPA analysis proteomics facilitates the elucidation of protein interactions and their functional roles in biological systems. This approach has broad applications in biomedical research, including studies on cancer, immune disorders, neurodegenerative diseases, and met......
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Fish proteomics is a scientific discipline that employs high-throughput proteomics technologies to systematically investigate the composition, structure, post-translational modifications, and interactions of proteins in fish. As a crucial branch of proteomics in aquatic biology, fish proteomics facilitates the analysis of fish physiological and biochemical processes while elucidating their molecular responses to environmental changes, nutritional regulation, immune challenges, and evolutionary pressur......
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• Identify Protein from Amino Acid Sequence
The ability to identify protein from amino acid sequence is a fundamental technique in proteomics research. By analyzing the composition and sequential arrangement of amino acids, this approach provides critical insights into protein structure and function. It plays a pivotal role in protein identification, functional characterization, post-translational modification (PTM) analysis, and the discovery of novel biomarkers. Given that protein function is inherently dictated by its amino acid sequence, th......
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• Hypothetical Protein Analysis
Hypothetical protein analysis is a key research strategy in proteomics, designed to identify and characterize proteins predicted to exist but not yet confirmed by experimental evidence. These proteins are typically inferred from genome annotations, transcriptomic data, or computational models predicting their potential presence under specific biological conditions. By integrating advanced mass spectrometry techniques with computational bioinformatics, researchers can systematically detect and characte......
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• Identification of New Drug Targets
The identification of new drug targets is a critical phase in drug discovery, aiming to identify and validate molecular targets that interact with therapeutic compounds and regulate specific physiological or pathological processes. These targets, including proteins, RNA molecules, receptors, and enzymes, play fundamental roles in disease onset and progression. Through systematic target identification, scientists can pinpoint key molecules associated with specific diseases and further investigate their......
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• Global Analysis of Protein Structural Changes in Complex Proteomes
The global analysis of protein structural changes in complex proteomes is a critical yet challenging task for understanding biological processes and disease mechanisms. This approach provides insights into protein function under various physiological and pathological conditions and elucidates their roles in cellular pathways. Investigating protein structural changes enables the identification of disease mechanisms, discovery of potential therapeutic targets, and optimization of drug design. Furthermor......
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• Global Site-Specific Analysis of Glycoprotein N-Glycan Processing
The global site-specific analysis of glycoprotein N-glycan processing is a powerful approach for characterizing the precise locations of N-glycan modifications in glycoproteins. This analytical method provides critical insights into glycoprotein biosynthesis, structural integrity, and functional roles at the molecular level. Glycoproteins are vital biomolecules found in cell membranes, extracellular matrices, and circulatory fluids. Their N-glycan modifications influence stability, molecular recogniti......
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Cancer biomarker discovery is a scientific approach that utilizes modern biotechnologies to identify molecular indicators associated with cancer onset, progression, and therapeutic response across multiple biological levels, including genomics, proteomics, and metabolomics. Cancer development is driven by complex genetic and environmental factors, accompanied by molecular alterations in signaling pathways, metabolic regulation, and immune evasion. These changes are often reflected in specific biomarke......
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