Resources

Proteomics Databases



Metabolomics Databases

• • Selected Reaction Monitoring Mass Spectrometry

  Selected reaction monitoring mass spectrometry is an analytical technique based on tandem mass spectrometry, offering high sensitivity and precise quantification. It is widely utilized in proteomics, metabolomics, pharmacokinetics, and environmental science. By leveraging the high selectivity of tandem mass spectrometry, SRM enables highly specific detection through precise selection of precursor ions and their characteristic fragment ions. Compared to conventional full-scan approaches, SRM significan......

• • Cell-Based High Throughput Screening

  Cell-based high throughput screening (CB-HTS) is a powerful tool for the rapid and efficient identification of bioactive compounds. By assessing cellular responses to chemical perturbations, CB-HTS enables the evaluation of potential pharmacological activity in a physiologically relevant context. This technology plays a critical role in early-stage drug discovery, allowing researchers to efficiently screen large compound libraries to identify candidate molecules with desirable biological activity. The......

• • Quantitative High Throughput Screening

  Quantitative high throughput screening (qHTS) is a powerful technology that enables the rapid, large-scale quantitative analysis of biological samples. It has been widely applied in various fields, including drug discovery, disease diagnosis, and environmental monitoring. In drug discovery, qHTS significantly enhances the efficiency of compound screening, expediting the identification of potential drug candidates. By providing comprehensive assessments of drug activity, toxicity, and metabolic stabili......

• • Small Molecule High Throughput Screening

  Small molecule high throughput screening (SM-HTS) is a pivotal technology for identifying and characterizing interactions between biological molecules and chemical small molecules. Its primary objective is to rapidly identify bioactive compounds through automated workflows and large-scale experimental designs. SM-HTS has broad applications across multiple disciplines, including medicine, agriculture, biotechnology, and environmental science.   In pharmaceutical research, SM-HTS is extensively employed......

• • Droplet Single Cell Sequencing

  Droplet single cell sequencing is a cutting-edge genomic technology designed to analyze genomic information at single-cell resolution. The core principle of this method involves encapsulating thousands of individual cells into microdroplets, which serve as isolated reaction chambers for sequencing. This approach enables high-throughput, high-resolution analysis of individual cells, facilitating a deeper understanding of cellular heterogeneity. Droplet single cell sequencing has found extensive applica......

• • Large Molecule Drug Discovery

  Large molecule drug discovery has become a central focus in modern biomedicine, dedicated to the screening, optimization, and development of biomolecules such as proteins, antibodies, nucleic acids, and peptides. This field encompasses a broad spectrum of therapeutics, including monoclonal antibodies, bispecific antibodies, antibody-drug conjugates (ADCs), fusion proteins, small interfering RNA (siRNA), and messenger RNA (mRNA). These drugs exert their effects by precisely targeting disease-associated......

• • Label Transfer Protein Interaction Analysis Overview

  Label transfer protein interaction analysis is an efficient technique for studying protein-protein interactions, widely applied in research fields such as cell biology, molecular biology, and proteomics. This method introduces specific labels (such as fluorescent labels, radioactive labels, or chemical labels) into the target protein or its interacting partners. By analyzing the transfer of these labels, protein-protein interactions can be revealed. When two proteins interact, the label on one protein......

• • Targeted Proteomics Analysis

  Targeted proteomics is a specialized branch of proteomics designed to facilitate precise analysis of specific proteins or proteomes. Unlike traditional discovery proteomics, which broadly surveys the proteome, targeted proteomics focuses on a predefined subset of proteins, allowing for highly sensitive and specific detection and quantification. This approach has extensive applications in biomarker validation, drug development, and disease mechanism studies. By employing targeted proteomics, researchers.....

• • BiFC Protein Interaction

  BiFC protein interaction is a fluorescence-based protein reconstitution technique used to study protein-protein interactions. This method exploits the fragmentable nature of fluorescent proteins, such as yellow fluorescent protein (YFP), green fluorescent protein (GFP), or red fluorescent protein (mCherry), by splitting them into two non-fluorescent fragments, which are individually fused with the proteins of interest. When these two proteins interact within the cell, the fluorescent protein fragments......

• • Immunoprecipitation Protein Interaction

  Immunoprecipitation protein interaction is a technique widely used in the fields of molecular biology and biochemistry, primarily employed to study protein-protein interactions. Through this technique, researchers can use specific antibodies to recognize and capture target proteins, precipitating them along with their interacting partners from complex cellular samples, thereby revealing protein interaction networks. The greatest advantage of immunoprecipitation Protein Interaction lies in its high..........