Resources

• • Mass Spectrometry Analysis of Protein Modifications from Acetylation to Phosphorylation

  Protein modification is an important biochemical process in living organisms, playing a vital role in regulating protein function, stability, and subcellular localization. This article will use mass spectrometry as a tool to delve into the detection methods for protein acetylation and phosphorylation modifications.   Protein Modification Protein modification is a common phenomenon in living organisms, affecting protein function and activity by altering their chemical properties.

• • How to Detect the Phosphorylation Level of Proteins

  The study of the phosphorylation state of proteins in the field of biological product proteomics is an important and challenging task. Protein phosphorylation is a key process in cell signal transduction that can regulate protein function, cell proliferation, apoptosis, and many other biological processes. Therefore, accurately detecting and quantifying the levels of protein phosphorylation is essential for understanding cell signaling networks and developing biopharmaceuticals.   Mass Spectrometry Ma......

• • How to Optimize Immunoprecipitation Co-IP Technology for Protein Interaction Research

  In biomedical research, understanding the network of protein interactions is crucial for revealing cellular signal transduction, disease mechanisms, and the development of biopharmaceuticals. Co-Immunoprecipitation (Co-IP) technology is a key method for studying protein interactions, helping scientists identify and analyze the interactions among proteins. However, due to sample complexity and differences in experimental conditions, this technology may face some challenges in practical applications.

• • Immunopeptiomics to Analyze the Function of Peptides From Samples to Results

  As advancements in technology continue to progress, the field of biomedical sciences has achieved rapid development. Among these, immunopeptidomics, as an important research field, provides us with a new perspective to unravel the mysteries of the immune system. This article will focus on the importance of immunopeptidomics, from sample collection, analysis methods, to the interpretation of polypeptide functions.

• • Serum Proteomics

  Serum proteomics is a science that studies all proteins in serum, which is of great importance for understanding the functions of biological systems and the occurrence of diseases. The development of serum proteomics analysis technology makes it possible for us to reveal the potential biomarkers in the proteome of biological systems, providing new possibilities for early diagnosis and treatment of diseases.

• • Plasma Proteomic Analysis Methods

  Plasma, the concentrated essence of the fluid in our bodies, contains more than 10,000 proteins. Fortunately, thanks to assiduously studied plasma proteomics, we can now peer into these microscopic worlds at incredibly fine levels of detail. But how to choose the appropriate method for plasma proteomic analysis?   Proteins are the primary carriers of life activities and are the fundamental building blocks of our life.

• • Cellular Proteomics Decipher Intracellular Protein-Protein Interaction Networks

  Cellular proteomics is an important branch of biology that studies the structure and function of all proteins within cells. These proteins interact with each other, forming a complex network that is vital to cellular life processes. Therefore, unravelling this network and understanding the interactions between proteins is crucial for our understanding of the nature of life and the development of new drugs.

• • How to Use Blood Proteomics to Analyze the Protein Expression of Biodiversity

  Blood proteomics is a major area of research in the field of biopharmaceuticals. It provides crucial information about various physiological and pathological processes within a biological organism through comprehensive and in-depth analyses of the proteins in the blood. Research in blood proteomics not only aids in understanding protein expression in biological diversity, but also provides key insights for early diagnosis and treatment of diseases.

• • Mechanism of Differential Protein Analysis

  Differential protein analysis enables researchers to detect changes in protein expression within organisms exposed to specific environments, disease states, or pharmacological treatments, providing insights into the roles proteins play in complex biological processes, employed to identify proteins that exhibit significant differences in expression levels under various conditions or among different sample groups.   The fundamental principle of differential protein analysis involves comparing the differ......

• • Acetylation Modification Diverse Site Analysis Methods

  Acetylated proteomics is a highly focused research direction in the field of biopharmaceutical proteomics. Protein acetylation modification plays an important role in cell function regulation. The diversity and complexity of acetylation modification make it a hot spot of research.    Acetylated proteomics is a comprehensive and systematic study of acetylated proteins, revealing the functions and mechanisms of acetylation modification in cell regulation. Acetylation modification not only regulates the ......