Resources

• • Mass Spectrometry Accelerates the Discovery of Proteomics Disease Biomarkers

  Proteomics is a binary proposition between the chicken and the egg. Our genes encode individual proteins that help form life; on the other hand, when life is threatened by disease, the composition of proteins in our body changes, which reflects our health status. Therefore, understanding proteomics in depth is not only important for scientists to understand the secrets of life, but also helps doctors discover and treat diseases.

• • Polysaccharidomics in Glycosylation Quality Control and Efficacy Research of Biologics

  Glycosylation modification is one of the common important quality attributes in biopharmaceuticals, which has a significant impact on drug activity, stability, and immunogenicity. Glycomics, as an emerging field for studying glycosylation modification, provides powerful tools and platforms for deciphering complex glycosylation modifications in biopharmaceuticals through the comprehensive use of analytical techniques and bioinformatics methods.

• • Key Role of PRM Validation in Proteomics

  In the field of biopharmaceutical research, we have high demands for the accuracy of data. However, in the field of proteomics, which involves a large amount of complex and ever-changing data, we face numerous challenges. In this context, PRM validation plays an indispensable role. In the following, we will explore the necessity of PRM validation and its role in proteomics.

• • A New Approach for Efficient Protein Analysis

  Proteomics, as an important branch of biological science, has been driving the development of the biopharmaceutical field. In recent years, with the advancement of technology, proteomics techniques have also been continuously updated, providing us with more efficient and accurate protein analysis methods.

• • Proteomics Unveiling the Cell Proteome

  The Importance of Proteomics Proteins, as the building blocks of life, are the main executors of cellular activities. The variations in the types, quantities, structures, and functions of proteins directly impact the life processes of organisms. Proteomics, the scientific study of proteins, investigates the expression, modifications, interactions, and functions of proteins in a comprehensive and systematic manner.

• • Comprehensive Analysis of Proteomics Research

  Proteomics, as an important branch of biological science, is a discipline that comprehensively studies the structure and function of all proteins in an organism. It focuses on proteins as the research object and uses high-throughput techniques to reveal protein expression, modification, interactions, and their functions in organisms.

• • Mass Spectrometry TMT Technology

  TMT mass spectrometry (Tandem Mass Tag) technology is a qualitative and quantitative peptide research technique based on mass spectrometry. TMT technology uses chemical labeling reagents to label peptides in whole protein extracts, enabling their separation in mass spectrometers and even distinguishing differences in single amino acid residues. This is a powerful tool for accurately identifying protein expression differences.

• • Insights into Amino Acid Content Determination Methods

  Amino Acids and the Origin of Life Amino acids, as the building blocks of life, are the fundamental elements that make up proteins. The types and proportions of amino acids determine the structure and function of proteins. Therefore, accurate determination of amino acid content is crucial for understanding protein conformation in living organisms.

• • The Differences Between Histone Ubiquitination and Phosphoproteomics

  Protein modification plays a crucial role in understanding cellular signaling and disease mechanisms in the field of biopharmaceuticals. Ubiquitination and phosphorylation are two common protein modification methods that play indispensable roles in cellular processes.

• • Studying Specific Acetylation Sites on Histones Using WB

  Histone acetylation is a common protein modification that changes the function and structure of proteins by adding acetyl groups to specific sites on the histone protein chain. Histone acetylation plays an important regulatory role in cells and is involved in regulating processes such as gene expression, cell cycle, and cell differentiation.