Resources

• • Main Types of Modifications on Histones

  Histone is one of the most important proteins in the cell nucleus, playing a crucial role in maintaining genome structure and function. However, histones are not static, as they can be regulated through a series of modifications that affect gene expression and chromatin state. This article will introduce the main types of histone modifications and explore the applications and prospects of glycan identification in research.

• • Glycosylation Identification of Recombinant Proteins

  Glycosylation is an important protein modification method that plays a key role in cellular signal transduction, protein stability, and functional regulation. By identifying glycosylation of recombinant proteins, researchers can explore new targets and further analyze the association between these targets and cellular function.

• • The Distribution and Functional Analysis of Acetylation Modification on Histones

  Acetylation modification is a common protein modification method, which refers to the addition of an acetyl group (CH3CO-) to the protein. This modification mainly occurs on histones, which are the major components of chromatin and play an important role in gene expression regulation.

• • What Common Techniques and Methods Are Used in Glycomics MS?

  Glycomics is the discipline that studies the composition, structure, and function of sugar molecules in living organisms. Sugar molecules play important roles in biological processes such as cell signaling, protein modification, and immune response. Glycomics research is significant for understanding disease mechanisms, drug development, and biotechnology. Mass spectrometry is one of the commonly used techniques in glycomics analysis.

• • How Does Glycomics Reveal the Full Picture of Protein Glycosylation

  Glycomics is a method of studying the structure and function of biomacromolecules (such as proteins, RNA, and DNA) in living organisms. It involves measuring the interactions between these macromolecules and other molecules to understand their structure and function. Protein glycosylation refers to the process of protein modification by attaching sugar or polysaccharide chains. This modification can alter the function of the protein, thereby affecting the overall functioning of the biological system.

• • Qualitative and Quantitative Study Techniques for Syrup Samples

  Carbohydrates are one of the most common organic molecules in living organisms and are essential components of biopharmaceuticals. Therefore, the analysis and study of carbohydrate composition are particularly important. This article will introduce the qualitative and quantitative research techniques for liquid sugar samples, helping readers better understand the methods of carbohydrate composition analysis.

• • Analysis of Protein Acetylation Modifications

  In the complex cellular processes, protein acetylation modification plays a crucial role, especially histone acetylation has the most profound impact. However, how can we quantitatively determine this important biological process? Today, let's explore the fascinating world of histone acetylation detection together.

• • Principle of Proteome Bioinformatic Analysis

  Proteomics is a field that studies the composition, structure, and function of all proteins in a cell, tissue, or organism. It has become a crucial tool in modern biological research for uncovering the functions of biological systems, disease mechanisms, drug targets, and more. Bioinformatic analysis of proteomics is the core step for systematically analyzing and interpreting proteomic data.

• • Mechanism of Immune Peptide Presentation in Immunopeptidomics

  Immunopeptidomics is a cutting-edge field that focuses on understanding the mechanisms of antigen presentation within the immune system, primarily by analyzing and identifying peptide fragments presented by Antigen-Presenting Cells (APCs). These peptides bind to Major Histocompatibility Complex (MHC) molecules and are displayed on the cell surface, initiating a specific immune response through T-cell recognition.

• • Application of Immunopeptidomics in Disease Therapy

  In recent years, immunopeptidomics has emerged as a crucial tool for studying the immune system and mechanisms of antigen presentation, showing promising potential in the field of disease therapy. Immunopeptidomics is the study of peptides bound to major histocompatibility complex (MHC) molecules and their presentation mechanisms.