Resources

• • Protein Identification Comprehensive Analysis

  Protein is one of the most fundamental constituents of biological organisms, and is critical for understanding the functions and disease mechanisms of organisms. Protein identification is a key technology that can aid scientists in recognizing and quantifying proteins in a sample. This article will comprehensively analyze the process and methods of protein identification from sample processing to minimal protein quantity determination.

• • Suitable Mass Spectrometry Methods for Detecting Protein Interactions

  Protein is one of the most important molecules in living organisms, playing a variety of functions within cells. The interaction between proteins is an essential component of maintaining cellular life activities. Therefore, studying protein interactions is crucial for understanding the mechanism of cellular life activities. Mass spectrometry technology is widely used in proteomics research and can be used to analyze protein interactions.

• • Mass Spectrometry Detection of Proteins

  Proteins within organisms are an integral part of cells and tissues, playing a crucial role in sustaining life. However, understanding the composition and functions of these proteins is not an easy task. Over the past few decades, scientists have continuously explored various methods to decipher the peptide composition and functions within organisms. Among these, mass spectrometry, a highly efficient and accurate analytical method, has revealed the mysterious veil of the protein world for us.

• • COIP Mass Spectrometry Methods

  Proteins are important functional molecules in biological organisms. They form complexes through interactions and participate in regulating cellular physiological processes. Studying the composition and structure of protein complexes is crucial for understanding cellular functions and disease mechanisms. The COIP mass spectrometry method, as a highly efficient protein complex analysis technology, has revealed the mystery of constructing protein complexes.

• • CD Circular Dichroism Spectroscopy Interpretation

  Circular Dichroism (CD) is a spectroscopic technique used to study the structure of biomacromolecules such as proteins and nucleic acids. Its principle is based on the differential absorption of left and right circularly polarized light by biomacromolecules. This difference reflects the three-dimensional structure of biomacromolecules, therefore, CD is widely used in the field of bio-pharmaceutical analysis.

• • Mass Spectrometry Identification of Protein-Protein Interactions

  Importance of Protein-Protein Interactions In biological tissues and cells, proteins serve as the foundation of life, implementing life processes through interactions with each other. The function of proteins often depends on the complexes they are part of and their environment, which are formed through interactions between proteins. Protein-protein interactions have always been an important area of biological research, especially in the field of biopharmaceutical research.

• • HDX-MS Data Interpretation

  Ion beam is a well-known type of electromagnetic wave, and the famous mass spectrometry technology is conducted with its aid. What we are going to introduce to you this time is a cutting-edge mass spectrometry technology — HDX MS. "You ask what this has to do with biopharmaceuticals?" There is much to tell!

• • Mass Spectrometry and Bioinformatics

  Proteins are important functional molecules in biological organisms, playing a key role in understanding biological processes and disease mechanisms. Mass spectrometry and bioinformatics, as two powerful analysis methods, can provide a wealth of protein information. However, the singular application of mass spectrometry or bioinformatics in protein analysis has some limitations.

• • Application of Mass Spectrometry in Drug Discovery

  Drug discovery is a complex and tedious process involving a large number of experiments and data analysis. In this process, proteins play a crucial role as drug targets. However, the accurate identification and characterization of proteins in drug development remains a challenging task. In this regard, the application of mass spectrometry technology provides effective assistance for drug discovery.

• • Proteomic Profiling of Exosomes from Plasma Samples

  Exosomes are small vesicles secreted by cells, typically ranging from 30 to 150 nm in diameter, with a membrane-bound structure. In recent years, exosomes have emerged as crucial mediators of intercellular communication, carrying molecules such as proteins, lipids, and nucleic acids that modulate physiological functions of recipient cells, either locally or distantly.