Resources
Proteomics Databases
Metabolomics Databases
-
• Quantitative Mass Spectrometry
Quantitative mass spectrometry is primarily employed to measure the concentrations of proteins or other molecular components in biological samples, providing insights into their roles in specific biological processes or disease states. This technique utilizes a mass spectrometer to analyze the mass, abundance, and other characteristics of target molecules with high sensitivity. By integrating standardized quantitative methods, it enables precise measurement of molecular information in complex biologic......
-
CD spectroscopy of proteins is a versatile and widely used technique for investigating the conformational and dynamic properties of biological macromolecules. By measuring the differential absorption of left- and right-handed circularly polarized light, it provides critical insights into molecular conformation. Since the secondary structure of proteins directly influences circular dichroism spectra, this method finds broad applications in monitoring conformational changes, studying stability, analyzin......
-
• Circular Dichroism for Proteins
Circular dichroism for proteins is a spectroscopic technique widely used to analyze the secondary structures of proteins, their conformational changes, and interactions with ligands. This method leverages the optical phenomenon of circular dichroism, which arises from the differential absorption of left- and right-handed circularly polarized light by chiral molecules. By recording CD spectra across various wavelengths, researchers can deduce the secondary structure composition of proteins, including α......
-
• Circular Dichroism CD Spectra
Circular dichroism CD spectra is an essential spectroscopic technique widely used to investigate molecular structures, leveraging the differential absorption of circularly polarized light to provide insights into molecular chirality and configuration. This technique plays a crucial role in studying biomacromolecules, particularly proteins and nucleic acids, under near-physiological and non-destructive conditions. Circular dichroism CD spectra is invaluable in protein research for determining secondary......
-
CD spectra of protein is a pivotal spectroscopic technique for exploring the structural properties of proteins. By measuring the differential absorption of left- and right-handed circularly polarized light, CD spectra offer detailed insights into the secondary structures of proteins. These secondary structures, including α-helices, β-sheets, and random coils, play crucial roles in determining protein function. Analyzing CD spectra of protein enables researchers to unravel intricate details about p......
-
• Circular Dichroism (CD) Spectroscopy
Circular dichroism (CD) spectroscopy is a fundamental spectroscopic tool widely employed for molecular structural analysis, especially the study of biomacromolecule conformations. The method utilizes the differential absorption of circularly polarized light to provide structural insights, making it particularly useful in characterizing the secondary structures of proteins and nucleic acids. Understanding such structural details is critical since the biological activity of these macromolecules depends ......
-
• Advancing Biomolecular Studies with Circular Dichroism CD Spectroscopy
Circular dichroism CD spectroscopy is a pivotal technique in molecular structure analysis, particularly for exploring the secondary structures of biomacromolecules. This spectroscopic method leverages the differential absorption of circularly polarized light to derive detailed structural information. Its application is especially prominent in analyzing proteins and nucleic acids. By measuring the spectral characteristics in the far-UV and near-UV regions, CD spectroscopy reveals critical data on α-hel......
-
• Advancing Drug Discovery with Activity-Based Protein Profiling
Activity-based protein profiling integrates proteomics technologies with bioactivity studies to investigate protein functionality and biological responses under disease or drug influence by detecting dynamic activity changes. Proteins are pivotal to cellular processes, with their functions often manifesting through activity, such as enzymatic catalysis, protein-protein interactions, and signal transduction. This profiling method leverages activity monitoring to elucidate the roles of proteins in compl......
-
• Unveiling Functional Proteomics with Activity-Based Protein Profiling
Activity-based protein profiling (ABPP) is a state-of-the-art technology that leverages small molecule probes to selectively label and analyze active proteins in biological systems. Through the integration of mass spectrometry, ABPP enables high-throughput functional studies of proteins, emphasizing their activity states rather than their abundance. This unique feature allows ABPP to uncover dynamic protein function and has become an indispensable tool in studying enzyme activity, identifying drug tar......
-
The Co IP assay is a cornerstone technique in studying protein-protein interactions, extensively applied across basic biology, drug discovery, and disease mechanism research. By leveraging this approach, researchers gain insights into intracellular protein functions, regulatory mechanisms of signaling pathways, and roles in pathological conditions. This technique capitalizes on the specific binding properties of antibodies to isolate target proteins and their associated complexes. Combining immunologi......
How to order?
