Resources

Proteomics Databases



Metabolomics Databases

• • Antigen Identification

  Antigen identification is a pivotal biotechnology technique focused on determining the identity and properties of specific antigens to elucidate their roles in immune responses, disease mechanisms, and drug development. Antigens, including proteins, peptides, carbohydrates, or nucleic acids, trigger specific immune responses. This process is indispensable in immunology and proteomics, particularly in vaccine development, cancer immunotherapy, and autoimmune disease research.   For instance, antigen id......

• • Peptide Quantification

  Peptide quantification is a proteomics technique used to precisely measure the concentration and dynamic changes of specific peptides or proteins in biological samples. This method enables researchers to uncover protein expression dynamics, elucidate molecular mechanisms underlying biological processes, and identify disease-related biomarkers. By providing quantitative data at the protein level, peptide quantification overcomes the limitations of traditional omics approaches, which often focus solely ......

• • Custom Peptide Synthesis Service

  Custom peptide synthesis service involves designing and producing peptides with specific sequences and properties tailored to meet precise experimental or industrial requirements. Peptides, composed of amino acids linked by peptide bonds, are essential biological molecules widely present in living systems, playing critical roles in diverse physiological processes. This service has become a cornerstone in advancing scientific research and industrial innovation.   In biomedical research, custom peptide ......

• • Kinome Profiling

  Kinome profiling is an emerging and rapidly advancing field in life sciences, dedicated to systematically studying protein kinases, including their expression, activity regulation, and functional roles in cellular signaling, metabolism, and disease progression. Protein kinases, responsible for catalyzing phosphorylation, regulate protein function, structure, and localization, thereby influencing diverse biological processes. The human kinome consists of over 500 kinase-coding genes, and their dysregul......

• • Target Identification and Validation

  Target identification and validation represent critical stages in modern life sciences research and drug discovery. These processes involve determining the relationship between specific biomolecules, such as proteins or nucleic acids, and diseases or biological functions through experimental and data-driven approaches. They further validate the feasibility and reliability of these molecules as therapeutic intervention points. Target identification focuses on identifying molecules closely linked to dis......

• • Amino Acid Analysis by LC-MS/MS

  Amino acid analysis by LC-MS/MS combines liquid chromatography (LC) with tandem mass spectrometry (MS/MS) to identify and quantify amino acids in complex biological samples. As the fundamental building blocks of proteins, amino acids play vital roles in metabolic pathways, serving as intermediates and precursors for neurotransmitters. This method offers precise quantitative insights into amino acid composition, proving essential in biomedical research, food science, agriculture, and environmental moni......

• • TMT Quantification

  TMT quantification (Tandem Mass Tag quantification) is a widely employed high-throughput technique in proteomics that enables relative quantification of proteins or peptides across multiple samples through isotopic labeling. This approach utilizes tandem mass spectrometry (MS/MS) to compare protein expression levels with high precision by incorporating distinct TMT tags into each sample. A key advantage of TMT quantification lies in its ability to analyze multiple samples simultaneously within a singl......

• • Advances in N Glycan Analysis Techniques

  N-glycan analysis is the systematic study of N-linked glycosylation modifications on proteins. N-glycans are attached to asparagine (Asn) residues via glycosidic bonds, with a typical structure initiated by N-acetylglucosamine (GlcNAc). These sugar chains can undergo further modifications and branching, forming complex polysaccharide structures. Glycosylation is a dynamic and reversible modification influenced by factors such as enzymatic activity, intracellular conditions, and pathological changes. D......

• • TurboID Proximity Labeling

  TurboID proximity labeling is an advanced technology designed to investigate protein-protein interactions and their spatial organization within cells. The technique operates by fusing a target protein with the TurboID tag, a highly efficient biotin ligase. In the presence of biotin, TurboID rapidly biotinylates proteins in close proximity, typically within minutes. These biotin-labeled proteins can then be purified using affinity-based methods, such as streptavidin-biotin capture, and identified throu......

• • Single-Cell TCR Sequencing

  Single-cell TCR sequencing is a genomic technique designed to characterize T cell receptor (TCR) sequences at single-cell resolution. T cell receptors, expressed on the surface of T cells, are responsible for antigen recognition and immune response initiation. The diversity of TCRs underpins the ability of T cells to recognize a wide array of antigens. Analyzing TCR sequences offers valuable insights into immune system functionality and disease mechanisms.   In tumor immunology, single-cell TCR sequen......